Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10879927 | 0.92 | LMNA (0.52) | CNR1CNR2SHBGESR1ESR2 | |
| SCHEMBL187807 | 0.92 | ESR1 (0.52) | CNR1CNR2SHBGESR1ESR2 | |
| SCHEMBL873489 | 0.89 | TSHR (0.52) | CNR1CNR2SHBGESR1ESR2 | |
| SCHEMBL13666515 | 0.89 | CNR1 (0.43) | CNR1CNR2SHBGESR1ESR2 | |
| SCHEMBL10476838 | 0.89 | SHBG (0.64) | CNR1CNR2SHBGESR1ESR2 | |
| SCHEMBL394785 | 0.87 | MAPT (0.52) | CNR1CNR2SHBGESR1ESR2 | |
| SCHEMBL186541 | 0.87 | CNR1 (0.42) | CNR1CNR2SHBGESR1ESR2 | |
| SCHEMBL3045994 | 0.87 | CNR1 (0.42) | CNR1CNR2SHBGESR1ESR2 | |
| SCHEMBL1807039 | 0.87 | MEN1 (0.56) | CNR1CNR2SHBGTSHRSLC6A2 | |
| SCHEMBL31556506 | 0.87 | CES2 (0.43) | CNR1CNR2TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890998-A2 | PROCESS FOR THE PREPARATION OF POLYISOCYANATES OF THE DIPHENYLMETHANE SERIES | HUNTSMAN INTERNATIONAL LLC (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006130405-A2 | PROCESS FOR THE PREPARATION OF POLYISOCYANATES OF THE DIPHENYLMETHANE SERIES | HUNTSMAN INTERNATIONAL LLC (US) | 2006-12-07 | — | — | WO | disclosed |
| WO-1999058607-A1 | POLYMER MIXTURES CONTAINING CARBON MONOXIDE/α-OLEFIN COPOLYMERS AND COPOLYMERS MADE OF VINYL AROMATIC COMPOUNDS AND VINYL CYANIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-18 | — | — | WO | disclosed |