Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15401669 | 0.95 | SIGMAR1 (0.38) | SIGMAR1SLC6A3SLC6A4DRD2RAD52 | |
| SCHEMBL15066275 | 0.93 | SIGMAR1 (0.37) | SIGMAR1SLC6A3SLC6A4DRD2RAD52 | |
| SCHEMBL13008040 | 0.88 | SIGMAR1 (0.36) | SIGMAR1SLC6A3SLC6A4DRD2SLC6A2 | |
| SCHEMBL19149177 | 0.85 | SIGMAR1 (0.35) | SIGMAR1SLC6A3SLC6A4DRD2SLC6A2 | |
| SCHEMBL13008047 | 0.84 | SIGMAR1 (0.34) | SIGMAR1SLC6A3SLC6A4DRD2SLC6A2 | |
| SCHEMBL13008048 | 0.82 | ACE2 (0.52) | SIGMAR1SLC6A3SLC6A4RAD52 | |
| SCHEMBL19071674 | 0.82 | SIGMAR1 (0.33) | SIGMAR1SLC6A3SLC6A4DRD2RAD52 | |
| SCHEMBL12677693 | 0.82 | KDM1A (0.37) | — | |
| SCHEMBL12156580 | 0.81 | DRD2 (0.39) | SIGMAR1SLC6A3SLC6A4DRD2SLC6A2 | |
| SCHEMBL1488103 | 0.81 | SIGMAR1 (0.38) | SIGMAR1SLC6A3SLC6A4DRD2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9644066-B2 | Cyclic amine compounds, compositions, and polyurethane foams made therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-05-09 | — | — | US | disclosed |
| EP-2797902-B1 | COMPOSITIONS CONTAINING CYCLIC AMINE COMPOUNDS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-04-26 | — | — | EP | disclosed |
| US-20150005404-A1 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC | 2015-01-01 | — | — | US | disclosed |
| EP-2797902-A2 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | Dow Global Technologies LLC (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013102097-A2 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005404-A1 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | PUF60, UFM1, POLM | SIGMAR1 2641/4885SLC6A3 3388/4885SLC6A4 4346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.