SCHEMBL15401669

SCHEMBL15401669

CCN(CC)CCN1CCN(CC)CC1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.38
RAD52 P43351 1/20 0.36
SLC6A3 Q01959 3/20 0.36
SLC6A4 P31645 2/20 0.36
DRD2 P14416 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15066275 0.98 SIGMAR1 (0.37) SIGMAR1RAD52SLC6A3SLC6A4DRD2
SCHEMBL15066355 0.95 SIGMAR1 (0.41) SIGMAR1RAD52SLC6A3SLC6A4DRD2
SCHEMBL13008040 0.88 SIGMAR1 (0.36) SIGMAR1RAD52SLC6A3SLC6A4DRD2
SCHEMBL12677693 0.86 KDM1A (0.37)
SCHEMBL12156580 0.86 DRD2 (0.39) SIGMAR1RAD52SLC6A3SLC6A4DRD2
SCHEMBL1488103 0.86 SIGMAR1 (0.38) SIGMAR1RAD52SLC6A3SLC6A4DRD2
SCHEMBL13701445 0.83 SIGMAR1 (0.50) SIGMAR1SLC6A3SLC6A4DRD2
SCHEMBL11955738 0.83 SIGMAR1 (0.46) SIGMAR1SLC6A3SLC6A4DRD2
SCHEMBL15401913 0.82 ALOX15 (0.36) SIGMAR1
SCHEMBL21267668 0.82 SIGMAR1 (0.36) SIGMAR1RAD52SLC6A3SLC6A4DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136434-B2 Polyamines, synthesis method thereof and use thereof for the selective elimination of H2S from a gaseous effluent comprising CO2 IFP Energies Nouvelles (FR) 2021-10-05 US claimed
CN-108602952-B Novel polyamines, method for their synthesis and their use for the removal of CO from a gas containing atmosphere2Selective removal of H from the gaseous effluent of2Use of S IFP 新能源公司 2021-03-12 CN claimed
US-10710021-B2 Polyamines, synthesis process thereof and use of same for the selective elimination of H2S from a gaseous effluent comprising CO2 IFP Energies Nouvelles (FR) 2020-07-14 US claimed
US-20200148824-A1 NOVEL POLYAMINES, SYNTHESIS METHOD THEREOF AND USE THEREOF FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 IFP Energies Nouvelles (FR) 2020-05-14 US claimed
EP-3645605-A1 NOVEL POLYAMINES, SYNTHESIS METHOD THEREOF AND USE THEREOF FOR THE SELECTIVE ELEMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING C02 IFP Energies nouvelles (FR) 2020-05-06 EP claimed
EP-3397671-B1 NOVEL POLYAMINES, SYNTHESIS PROCESS THEREOF AND USE OF SAME FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 IFP ENERGIES NOW (FR) 2020-02-12 EP claimed
EP-3083492-B1 METHOD FOR PURIFYING SYNTHESIS GAS BY AMINE SCRUBBING USING AQUEOUS AMINE SOLUTIONS AXENS (FR) 2019-04-17 EP claimed
US-20180369743-A1 NOVEL POLYAMINES, SYNTHESIS PROCESS THEREOF AND USE OF SAME FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 IFP Energies Nouvelles (FR) 2018-12-27 US claimed
WO-2018224350-A1 NOVEL POLYAMINES, SYNTHESIS METHOD THEREOF AND USE THEREOF FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 IFP Energies Nouvelles (FR) 2018-12-13 WO claimed
EP-3397671-A1 NOVEL POLYAMINES, SYNTHESIS PROCESS THEREOF AND USE OF SAME FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 IFP Energies nouvelles (FR) 2018-11-07 EP claimed
US-10118824-B2 Process for purifying synthesis gas by washing with aqueous solutions of amines AVRIL (FR) 2018-11-06 US claimed
WO-2017097716-A1 NOVEL POLYAMINES, SYNTHESIS PROCESS THEREOF AND USE OF SAME FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 IFP Energies Nouvelles (FR) 2017-06-15 WO claimed
US-20160368767-A1 PROCESS FOR PURIFYING SYNTHESIS GAS BY WASHING WITH AQUEOUS SOLUTIONS OF AMINES AVRIL (FR) 2016-12-22 US claimed
EP-3083492-A1 METHOD FOR PURIFYING SYNTHETIC GAS BY AMINE SCRUBBING USING AQUEOUS AMINE SOLUTIONS AXENS (FR) 2016-10-26 EP claimed
WO-2016142126-A1 NOVEL TERTIARY POLYETHER ALKANOLAMINES, METHOD FOR SYNTHESIS THEREOF, AND USE OF SAME FOR THE SELECTIVE REMOVAL OF THE HYDROGEN SULPHIDE FROM A GAS EFFLUENT COMPRISING CARBON DIOXIDE IFP Energies Nouvelles (FR) 2016-09-15 WO claimed
WO-2016142125-A1 ABSORBENT SOLUTION BASED ON AMINES COMPRISING A TERTIARY POLYETHERALKANOLAMINE, AND PROCESS FOR SELECTIVE ELIMINATION OF HYDROGEN SULPHIDE FROM A GASEOUS EFFLUENT COMPRISING CARBON DIOXIDE IFP Energies Nouvelles (FR) 2016-09-15 WO claimed
WO-2014001669-A1 ABSORBENT SOLUTION CONTAINING AMINES FROM THE AMINOALKYLPIPERAZINE FAMILY, AND METHOD FOR REMOVING ACID COMPOUNDS FROM A GASEOUS EFFLUENT USING SUCH A SOLUTION IFP Energies Nouvelles (FR) 2014-01-03 WO claimed
US-12138583-B2 Process for removal of acid gases from a fluid stream with a liquid absorbent comprising a piperazine ring BASF SE (DE) 2024-11-12 US disclosed
WO-2014001669-A1 ABSORBENT SOLUTION CONTAINING AMINES FROM THE AMINOALKYLPIPERAZINE FAMILY, AND METHOD FOR REMOVING ACID COMPOUNDS FROM A GASEOUS EFFLUENT USING SUCH A SOLUTION IFP Energies Nouvelles (FR) 2014-01-03 WO disclosed
WO-2014001669-A1 ABSORBENT SOLUTION CONTAINING AMINES FROM THE AMINOALKYLPIPERAZINE FAMILY, AND METHOD FOR REMOVING ACID COMPOUNDS FROM A GASEOUS EFFLUENT USING SUCH A SOLUTION IFP Energies Nouvelles (FR) 2014-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12138583-B2 Process for removal of acid gases from a fluid stream with a liquid absorbent comprising a piperazine ring AVPR2, HRH2, SLC43A1 SIGMAR1 470/4885RAD52 1044/4885SLC6A3 574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.