SCHEMBL15066601

SCHEMBL15066601

[O-][n+]1c(-c2ccccc2O)ccc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.44
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 2/20 0.36
BCL2L1 Q07817 1/20 0.36
ESR2 Q92731 1/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
POLB P06746 2/20 0.35
CASP6 P55212 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 3/20 0.33
MAPT P10636 3/20 0.33
RECQL P46063 2/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10493681 0.80 ATM (0.58) ATMNPC1RAB9AALDH1A1HSD17B10
SCHEMBL8980498 0.73 ATM (0.50) ATMNPC1RAB9AALDH1A1MEN1
SCHEMBL4145326 0.72 ATM (0.54) ATMNPC1RAB9AMEN1KMT2A
SCHEMBL3111168 0.71 ATM (0.40) ATMALDH1A1HPGDHSD17B10BCL2L1
SCHEMBL28438628 0.68 RAB9A (0.45) ATMNPC1RAB9AALDH1A1HPGD
SCHEMBL16243905 0.67 ATM (0.42) ATMNPC1RAB9AALDH1A1HPGD
SCHEMBL3443794 0.67 KDM4E (0.43) ATMNPC1RAB9AALDH1A1HPGD
Naphthalene SCHEMBL10525551 0.66 ALDH1A1 (0.57) NPC1RAB9AALDH1A1HPGDHSD17B10
SCHEMBL28745961 0.66 ATM (0.61) ATMNPC1RAB9AALDH1A1HPGD
SCHEMBL15780722 0.66 ATM (0.61) ATMNPC1RAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3074482-A1 ENCODED CHROMOPHORIC POLYMER PARTICLES University Of Washington Through Its Center For Commercialization (US) 2016-10-05 EP claimed
WO-2015081126-A1 ENCODED CHROMOPHORIC POLYMER PARTICLES UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2015-06-04 WO claimed
US-11697713-B2 Chromophoric polymer dots with narrow-band emission UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2023-07-11 US disclosed
US-11674964-B2 Encoded chromophoric polymer particles and methods of use thereof UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2023-06-13 US disclosed
US-11221336-B2 Encoded chromophoric polymer particles and methods of use thereof UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2022-01-11 US disclosed
EP-3521399-B1 ENCODED CHROMOPHORIC POLYMER PARTICLES UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2021-01-27 EP disclosed
EP-3718573-A1 CHROMOPHORIC POLYMER DOTS WITH NARROW-BAND EMISSION University of Washington Through Its Center for Commercialization (US) 2020-10-07 EP disclosed
US-10444243-B2 Encoded chromophoric polymer particles and methods of use thereof UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2019-10-15 US disclosed
EP-3074482-B1 ENCODED CHROMOPHORIC POLYMER PARTICLES UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2019-09-18 EP disclosed
EP-3521399-A1 ENCODED CHROMOPHORIC POLYMER PARTICLES University of Washington through its Center for Commercialization (US) 2019-08-07 EP disclosed
US-20190106542-A1 CHROMOPHORIC POLYMER DOTS WITH NARROW-BAND EMISSION UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2019-04-11 US disclosed
US-10150841-B2 Chromophoric polymer dots with narrow-band emission UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2018-12-11 US disclosed
US-20170003293-A1 ENCODED CHROMOPHORIC POLYMER PARTICLES AND METHODS OF USE THEREOF UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2017-01-05 US disclosed
EP-3074482-A1 ENCODED CHROMOPHORIC POLYMER PARTICLES University Of Washington Through Its Center For Commercialization (US) 2016-10-05 EP disclosed
WO-2015081126-A1 ENCODED CHROMOPHORIC POLYMER PARTICLES UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2015-06-04 WO disclosed
US-20140350183-A1 CHROMOPHORIC POLYMER DOTS WITH NARROW-BAND EMISSION UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2014-11-27 US disclosed
EP-2797635-A2 CHROMOPHORIC POLYMER DOTS WITH NARROW-BAND EMISSION University of Washington Through Its Center for Commercialization (US) 2014-11-05 EP disclosed
WO-2013101902-A2 CHROMOPHORIC POLYMER DOTS WITH NARROW-BAND EMISSION UNIVERSITY OF WASHINGTON, THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2013-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190106542-A1 CHROMOPHORIC POLYMER DOTS WITH NARROW-BAND EMISSION CDYL, PCBP1, CACYBP ATM 3912/4885NPC1 2924/4885RAB9A 1372/4885
US-11697713-B2 Chromophoric polymer dots with narrow-band emission CDYL, PCBP1, CACYBP ATM 3912/4885NPC1 2924/4885RAB9A 1372/4885
US-10150841-B2 Chromophoric polymer dots with narrow-band emission CDYL, PCBP1, CACYBP ATM 3912/4885NPC1 2924/4885RAB9A 1372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.