Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 8/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 5/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2242176 | 0.83 | TP53 (0.44) | FAAHEPHX1FUCA1CES1CES2 | |
| Trifluoroacetic Acid SCHEMBL31031817 | 0.82 | FAAH (0.42) | CA2FAAHEPHX1CES1CES2 | |
| Trifluoroacetic Acid SCHEMBL28336879 | 0.82 | CA2 (0.47) | CA2EPHX1FUCA1CES1MEN1 | |
| Trifluoroacetic Acid SCHEMBL27841664 | 0.82 | FAAH (0.42) | CA2FAAHEPHX1CES1CES2 | |
| Trifluoroacetic Acid SCHEMBL15711042 | 0.79 | FAAH (0.46) | FAAHEPHX1FUCA1CES1CES2 | |
| Trifluoroacetic Acid SCHEMBL3794549 | 0.79 | FAAH (0.40) | FAAHFUCA1CES1CES2MEN1 | |
| Trifluoroacetic Acid SCHEMBL281599 | 0.79 | FAAH (0.40) | FAAHFUCA1CES1CES2MEN1 | |
| Trifluoroacetic Acid SCHEMBL30324569 | 0.79 | FAAH (0.40) | FAAHFUCA1CES1CES2MEN1 | |
| Trifluoroacetic Acid SCHEMBL6273587 | 0.79 | HDAC4 (0.39) | FAAHEPHX1FUCA1CES1CES2 | |
| Trifluoroacetic Acid SCHEMBL28399119 | 0.79 | TP53 (0.40) | FAAHEPHX1FUCA1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556158-B2 | Fungicidal 3-[(pyridin-2-ylmethoxyimino)(phenyl)methyl]-2-substituted-1,2,4-oxadiazol-5(2H)-one derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| CN-104470896-B | Fungicidal 3- [ (pyridin-2-ylmethoxyimino) (phenyl) methyl ] -2-substituted-1, 2, 4-oxadiazol-5 (2H) -one derivatives | 拜耳知识产权有限责任公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-104039769-B | 3-[(1,3-thiazole-4-yl methoxyimino) (phenyl) methyl]-2-substituted-1,2,4-diazole-5 (2H) the-one derivant of antifungal | 拜耳知识产权有限责任公司 | 2016-10-19 | — | — | CN | disclosed |
| US-9326515-B2 | Fungicidal 3-[(1,3-thiazol-4-ylmethoxyimino)(phenyl)methyl]-2-substituted-1,2,4-oxadiazol-5(2H)-one derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-03 | — | — | US | disclosed |
| EP-2797891-B1 | FUNGICIDAL 3-[(PYRIDIN-2-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | BAYER IP GMBH (DE) | 2015-09-30 | — | — | EP | disclosed |
| EP-2797895-B1 | FUNGICIDAL 3-[(1,3-THIAZOL-4-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-05 | — | — | EP | disclosed |
| CN-104470896-A | Fungicidal 3- [ (pyridin-2-ylmethoxyimino) (phenyl) methyl ] -2-substituted-1, 2, 4-oxadiazol-5 (2H) -one derivatives | BAYER IP GMBH | 2015-03-25 | — | — | CN | disclosed |
| US-20150031730-A1 | FUNGICIDAL 3-[(1,3-THIAZOL-4-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| US-20140350058-A1 | FUNGICIDAL 3-[(PYRIDIN-2-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-11-27 | — | — | US | disclosed |
| EP-2797895-A1 | FUNGICIDAL 3-[(1,3-THIAZOL-4-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2014-11-05 | — | — | EP | disclosed |
| EP-2797891-A1 | FUNGICIDAL 3-[(PYRIDIN-2-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013098146-A1 | FUNGICIDAL 3-[(1,3-THIAZOL-4-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | WO | disclosed |
| WO-2013098147-A1 | FUNGICIDAL 3-[(PYRIDIN-2-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350058-A1 | FUNGICIDAL 3-[(PYRIDIN-2-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | CYP51A1, AZI2, PNPO | CA2 1754/4885FAAH 4169/4885EPHX1 893/4885 |
| US-20150031730-A1 | FUNGICIDAL 3-[(1,3-THIAZOL-4-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | CYP51A1, TH, CYP4X1 | CA2 965/4885FAAH 4512/4885EPHX1 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.