Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067309 | 1.00 | HTT (0.42) | HTTHPGDMAPTL3MBTL1MEN1 | |
| SCHEMBL15067321 | 0.78 | FGF23 (0.43) | HTTHPGDMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL15067322 | 0.78 | FGF23 (0.43) | HTTHPGDMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL16395323 | 0.78 | LMNA (0.42) | HTTHPGDMAPTL3MBTL1MEN1 | |
| SCHEMBL16395321 | 0.78 | LMNA (0.42) | HTTHPGDMAPTL3MBTL1MEN1 | |
| SCHEMBL15067998 | 0.75 | SRC (0.33) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL15067999 | 0.75 | SRC (0.33) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL9512596 | 0.74 | — | — | |
| SCHEMBL6738745 | 0.74 | — | — | |
| SCHEMBL15066800 | 0.73 | HPGD (0.35) | HTTHPGDMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10426169-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-10-01 | — | — | US | disclosed |
| EP-2921484-B1 | OXAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2921485-B1 | ISOXAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | disclosed |
| US-20180103641-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-19 | — | — | US | disclosed |
| EP-2921495-B1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| EP-2921492-B1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES | BAYER IP GMBH (DE) | 2017-09-06 | — | — | EP | disclosed |
| EP-2921491-B1 | INTERMEDIATES FOR THE PRODUCTION OF HETEROARYLPIPERIDINE AND - HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH (DE) | 2017-08-16 | — | — | EP | disclosed |
| EP-2921493-B1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES | BAYER IP GMBH (DE) | 2017-08-16 | — | — | EP | disclosed |
| US-20160200720-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-07-14 | — | — | US | disclosed |
| US-9375009-B2 | Heteroarylpiperidine and piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| EP-2921484-A1 | OXAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921493-A1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921495-A1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921492-A1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921491-A1 | INTERMEDIATES FOR THE PRODUCTION OF HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921485-A1 | ISOXAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921481-A1 | 4-PIPERIDINE CARBOXYLIC ACID DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| US-20150024935-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-22 | — | — | US | disclosed |
| EP-2797899-A2 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013098229-A2 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200720-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | RB1, RBX1, RRP12 | HTT 2141/4885HPGD 3059/4885MAPT 4074/4885 |
| US-10426169-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | RB1, RBX1, RRP12 | HTT 2177/4885HPGD 3001/4885MAPT 4047/4885 |
| US-20180103641-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | RB1, RBX1, RRP12 | HTT 2177/4885HPGD 3001/4885MAPT 4047/4885 |
| US-20150024935-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | RB1, RBX1, RRP12 | HTT 2141/4885HPGD 3059/4885MAPT 4074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.