SCHEMBL15067321

SCHEMBL15067321

Cc1[c]cccc1/C=N\O

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FGF23 Q9GZV9 2/20 0.43
LMNA P02545 4/20 0.41
ALOX12 P18054 1/20 0.41
HPGD P15428 5/20 0.40
MAPT P10636 1/20 0.40
ALDH1A1 P00352 4/20 0.38
HTT P42858 2/20 0.38
MAPK1 P28482 2/20 0.36
USP2 O75604 1/20 0.36
TSHR P16473 3/20 0.36
ACHE P22303 2/20 0.36
HRH1 P35367 1/20 0.36
PDE4D Q08499 1/20 0.36
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15067322 1.00 FGF23 (0.43) FGF23LMNAALOX12HPGDMAPT
SCHEMBL15067309 0.78 HTT (0.42) FGF23LMNAALOX12HPGDMAPT
SCHEMBL15067307 0.78 HTT (0.42) FGF23LMNAALOX12HPGDMAPT
SCHEMBL15067327 0.77 SRC (0.33) L3MBTL1
SCHEMBL15067329 0.77 SRC (0.33) L3MBTL1
SCHEMBL3478144 0.77
SCHEMBL16395323 0.76 LMNA (0.42) FGF23LMNAALOX12HPGDMAPT
SCHEMBL16395321 0.76 LMNA (0.42) FGF23LMNAALOX12HPGDMAPT
SCHEMBL5840808 0.72
SCHEMBL15067627 0.72 ACHE (0.36) FGF23LMNAALOX12HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10426169-B2 Heteroarylpiperidine and -piperazine derivatives as fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-10-01 US disclosed
EP-2921484-B1 OXAZOLE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2018-07-18 EP disclosed
EP-2921485-B1 ISOXAZOLE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2018-07-18 EP disclosed
US-20180103641-A1 HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-04-19 US disclosed
EP-2921495-B1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES BAYER IP GMBH (DE) 2018-03-28 EP disclosed
EP-2921492-B1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES BAYER IP GMBH (DE) 2017-09-06 EP disclosed
EP-2921493-B1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES BAYER IP GMBH (DE) 2017-08-16 EP disclosed
EP-2921491-B1 INTERMEDIATES FOR THE PRODUCTION OF HETEROARYLPIPERIDINE AND - HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES BAYER IP GMBH (DE) 2017-08-16 EP disclosed
US-20160200720-A1 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-07-14 US disclosed
US-9375009-B2 Heteroarylpiperidine and piperazine derivatives as fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-06-28 US disclosed
EP-2921495-A1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921492-A1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921481-A1 4-PIPERIDINE CARBOXYLIC ACID DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921485-A1 ISOXAZOLE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921494-A1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921491-A1 INTERMEDIATES FOR THE PRODUCTION OF HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921484-A1 OXAZOLE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
US-20150024935-A1 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-01-22 US disclosed
EP-2797899-A2 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES Bayer Intellectual Property GmbH (DE) 2014-11-05 EP disclosed
WO-2013098229-A2 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160200720-A1 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES RB1, RBX1, RRP12 FGF23 4644/4885LMNA 3567/4885ALOX12 3619/4885
US-10426169-B2 Heteroarylpiperidine and -piperazine derivatives as fungicides RB1, RBX1, RRP12 FGF23 4671/4885LMNA 3561/4885ALOX12 3575/4885
US-20180103641-A1 HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES RB1, RBX1, RRP12 FGF23 4671/4885LMNA 3561/4885ALOX12 3575/4885
US-20150024935-A1 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES RB1, RBX1, RRP12 FGF23 4644/4885LMNA 3567/4885ALOX12 3619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.