SCHEMBL1506746

SCHEMBL1506746

C=C(C)C(=O)OC1(C2(O)CC2C)CC1C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9422166 0.80 ALOX15 (0.37)
SCHEMBL17974552 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL27484483 0.71 ALOX15 (0.33) ALDH1A1
SCHEMBL11230563 0.70 ALDH1A1 (0.35) ALDH1A1
SCHEMBL7942993 0.70 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL3281463 0.68 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL18068501 0.68 ALDH1A1 (0.31) ALDH1A1
SCHEMBL25477401 0.68 NAAA (0.36) ALDH1A1TSHR
SCHEMBL6800120 0.68 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL6048958 0.68 ALDH1A1 (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2298820-B1 POROUS RESIN BEAD AND METHOD FOR PRODUCING NUCLEIC ACID USING THE SAME NITTO DENKO CORP (JP) 2020-11-04 EP disclosed
EP-2298821-B1 POROUS RESIN BEAD AND METHOD FOR PRODUCING NUCLEIC ACID USING THE SAME NITTO DENKO CORP (JP) 2020-07-29 EP disclosed
EP-2886564-B1 Porous resin bead and production method of nucleic acid by using same NITTO DENKO CORP (JP) 2016-09-21 EP disclosed
EP-2886564-A1 Porous resin bead and production method of nucleic acid by using same Nitto Denko Corporation (JP) 2015-06-24 EP disclosed
US-20150152234-A1 POROUS RESIN BEAD AND PRODUCTION METHOD OF NUCLEIC ACID BY USING SAME NITTO DENKO CORPORATION (JP) 2015-06-04 US disclosed
US-8802745-B2 Porous resin bead and method for producing nucleic acid using the same NITTO DENKO CORPORATION (JP) 2014-08-12 US disclosed
US-8653152-B2 Porous resin bead and method for producing nucleic acid using the same NITTO DENKO CORPORATION (JP) 2014-02-18 US disclosed
EP-2298821-A1 Porous Resin Bead and Method for Producing Nucleic Acid Using the Same Nitto Denko Corporation (JP) 2011-03-23 EP disclosed
EP-2298820-A1 Porous Resin Bead and Method for Producing Nucleic Acid Using the Same Nitto Denko Corporation (JP) 2011-03-23 EP disclosed
US-20110065822-A1 POROUS RESIN BEAD AND METHOD FOR PRODUCING NUCLEIC ACID USING THE SAME NITTO DENKO CORPORATION (JP) 2011-03-17 US disclosed
US-20110065818-A1 POROUS RESIN BEAD AND METHOD FOR PRODUCING NUCLEIC ACID USING THE SAME NITTO DENKO CORPORATION (JP) 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110065822-A1 POROUS RESIN BEAD AND METHOD FOR PRODUCING NUCLEIC ACID USING THE SAME PCNA, PARN, PHAX ALDH1A1 3496/4885TSHR 3962/4885
US-20110065818-A1 POROUS RESIN BEAD AND METHOD FOR PRODUCING NUCLEIC ACID USING THE SAME PCNA, ARID2, PARN ALDH1A1 3309/4885TSHR 3703/4885
US-20150152234-A1 POROUS RESIN BEAD AND PRODUCTION METHOD OF NUCLEIC ACID BY USING SAME PCNA, ELL, NUP205 ALDH1A1 3586/4885TSHR 4462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.