Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067485 | 1.00 | EGFR (0.33) | EGFRERBB2SRCKDRCHRM2 | |
| SCHEMBL15067990 | 0.79 | SRC (0.30) | SRC | |
| SCHEMBL15067988 | 0.79 | SRC (0.30) | SRC | |
| SCHEMBL13128156 | 0.77 | SMN1; SMN2 (0.42) | EGFRERBB2SRC | |
| SCHEMBL597572 | 0.73 | SRC (0.33) | SRC | |
| SCHEMBL597573 | 0.73 | SRC (0.33) | SRC | |
| SCHEMBL15067223 | 0.71 | ACHE (0.34) | — | |
| SCHEMBL15067226 | 0.71 | ACHE (0.34) | — | |
| SCHEMBL12724691 | 0.71 | EGFR (0.33) | EGFRERBB2SRCKDRCHRM2 | |
| SCHEMBL12763596 | 0.71 | EGFR (0.36) | EGFRERBB2SRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266382-B | Heteroarylpiperidine and piperazine derivatives as fungicides | 拜耳知识产权有限责任公司 | 2020-10-27 | — | — | CN | disclosed |
| US-10426169-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-10-01 | — | — | US | disclosed |
| US-20190023658-A1 | SUBSTITUTED 2-DIFLUOROMETHYL-NICOTIN(THIO)CARBOXANILIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-24 | — | — | US | disclosed |
| EP-2921484-B1 | OXAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2921485-B1 | ISOXAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | disclosed |
| US-20180103641-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-19 | — | — | US | disclosed |
| EP-2921495-B1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| CN-107266382-A | It is used as the heteroaryl piperidine and heteroaryl based piperazine derivative of bactericide | 拜耳知识产权有限责任公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-107266383-A | It is used as the heteroaryl piperidine and heteroaryl based piperazine derivative of bactericide | 拜耳知识产权有限责任公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-107253947-A | It is used as the heteroaryl piperidine and heteroaryl based piperazine derivative of bactericide | 拜耳知识产权有限责任公司 | 2017-10-17 | — | — | CN | disclosed |
| EP-2921495-A1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921491-A1 | INTERMEDIATES FOR THE PRODUCTION OF HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921492-A1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921493-A1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921485-A1 | ISOXAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921481-A1 | 4-PIPERIDINE CARBOXYLIC ACID DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| US-20150024935-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-22 | — | — | US | disclosed |
| EP-2797899-A2 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2014-11-05 | — | — | EP | disclosed |
| CN-104011032-A | Heteroarylpiperidine and piperazine derivatives as fungicides | BAYER IP GMBH | 2014-08-27 | — | — | CN | disclosed |
| WO-2013098229-A2 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10426169-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | RB1, RBX1, RRP12 | EGFR 4464/4885ERBB2 2837/4885SRC 2921/4885 |
| US-20180103641-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | RB1, RBX1, RRP12 | EGFR 4464/4885ERBB2 2837/4885SRC 2921/4885 |
| US-20150024935-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | RB1, RBX1, RRP12 | EGFR 4431/4885ERBB2 2740/4885SRC 2998/4885 |
| US-20190023658-A1 | SUBSTITUTED 2-DIFLUOROMETHYL-NICOTIN(THIO)CARBOXANILIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | NAPRT, BLVRB, CBR3 | EGFR 1666/4885ERBB2 433/4885SRC 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.