Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563927 | 1.00 | HSD17B10 (0.60) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL29953603 | 0.93 | HSD17B10 (0.56) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL7598992 | 0.86 | HSD17B10 (0.46) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL1506769 | 0.83 | HSD17B10 (0.58) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL3293879 | 0.83 | ALDH1A1 (0.44) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3299164 | 0.82 | KMT2A (0.45) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL6629135 | 0.82 | AKR1C3 (0.47) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL29404347 | 0.81 | HSD17B10 (0.78) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL7624693 | 0.81 | HSD17B10 (0.78) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| Benzene SCHEMBL28110156 | 0.81 | HSD17B10 (0.78) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737442-B1 | AGONISTS OF A BITTER TASTE RECEPTOR AND USES THEREOF | DEUTSCHES INST FÜR ERNÄHRUNGSFORSCHUNG STIFTUNG DES ÖFFENTLICHEN RECHTS VERTRETEN DURCH DEN STIFTUNG (DE) | 2015-01-07 | — | — | EP | claimed |
| US-20130237734-A1 | Aromatization Catalyst and Methods of Preparing Same | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-09-12 | — | — | US | claimed |
| US-8158372-B2 | Agonists of a bitter taste receptor and uses thereof | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POTSDAM-REHBRÜCKE (DE) | 2012-04-17 | — | — | US | claimed |
| JP-4812752-B2 | — | — | 2011-11-09 | — | — | JP | claimed |
| US-20100056621-A1 | AGONISTS OF A BITTER TASTE RECEPTOR AND USES THEREOF | DEUTSCHES INSTITUT FUR ERNAHRUNGSFORSCHUNG (DE) | 2010-03-04 | — | — | US | claimed |
| EP-1737442-A1 | AGONISTS OF A BITTER TASTE RECEPTOR AND USES THEREOF | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG - STIFTUNG DES ÖFFENTLICHEN RECHTS - VERTRETEN DURCH DEN STIFTUNGSVORSTAND (DE) | 2007-01-03 | — | — | EP | claimed |
| US-20060084176-A1 | Detection of uronium salts | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-04-20 | — | — | US | claimed |
| WO-2005102311-A1 | AGONISTS OF A BITTER TASTE RECEPTOR AND USES THEREOF | Deutsches Institut für Ernährungsforschung (DE) | 2005-11-03 | — | — | WO | claimed |
| US-6946025-B2 | Process for preparing tetra-amide compounds | XEROX CORPORATION (US) | 2005-09-20 | — | — | US | claimed |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | XEROX CORPORATION | 2005-04-28 | — | — | US | claimed |
| US-3933849-A | INDICATOR DYES AS OPTICAL FILTER AGENTS | POLAROID CORPORATION (US) | 1976-01-20 | — | — | US | claimed |
| US-3931228-A | Process for preparing phthalide and naphthalide indicator dyes | POLAROID CORPORATION (US) | 1976-01-06 | — | — | US | claimed |
| CN-113889621-B | Binder, negative electrode and lithium ion battery | 比亚迪股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| US-11554280-B2 | Long-term fire retardant with corrosion inhibitors and methods for making and using same | FRS GROUP, LLC (US) | 2023-01-17 | — | — | US | disclosed |
| US-20220080242-A1 | LONG-TERM FIRE RETARDANT WITH CORROSION INHIBITORS AND METHODS FOR MAKING AND USING SAME | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2022-03-17 | — | — | US | disclosed |
| CN-113889621-A | Binder, negative electrode and lithium ion battery | 比亚迪股份有限公司 | 2022-01-04 | — | — | CN | disclosed |
| US-3931228-A | Process for preparing phthalide and naphthalide indicator dyes | POLAROID CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931228-A | Process for preparing phthalide and naphthalide indicator dyes | POLAROID CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
| US-3816453-A | PROCESS FOR PREPARING NAPHTHALIDE INDICATOR DYES | POLAROID CORP | 1974-06-11 | — | — | US | disclosed |
| US-3728384-A | METHOD OF PRODUCING 1,8-NAPHTHALDEHYDE MONOCARBOXYLIC | NII SINT SPIRTOV | 1973-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090690-A1 | Process for preparing tetra-amide compounds | TAF9, TAF5, TAF1 | HSD17B10 2365/4885NR4A1 1369/4885NR4A2 2413/4885 |
| US-20100056621-A1 | AGONISTS OF A BITTER TASTE RECEPTOR AND USES THEREOF | TAS2R4, TAS2R30, TAS2R40 | HSD17B10 2787/4885NR4A1 1140/4885NR4A2 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.