Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320647 | 0.88 | RXRA (0.47) | RXRATDP1ALDH1A1MAPK1CA12 | |
| SCHEMBL2812534 | 0.84 | RXRA (0.52) | RXRATDP1ALDH1A1MAPK1CA12 | |
| SCHEMBL10822265 | 0.79 | RXRA (0.48) | RXRATDP1ALDH1A1MAPK1CA12 | |
| SCHEMBL6489983 | 0.78 | RXRA (0.47) | RXRATDP1ALDH1A1MAPK1CA12 | |
| SCHEMBL433187 | 0.77 | MAPT (0.45) | ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL30195971 | 0.75 | RXRA (0.64) | RXRATDP1ALDH1A1MAPK1SSTR5 | |
| SCHEMBL14898029 | 0.75 | RXRA (0.50) | RXRATDP1ALDH1A1MAPK1CA12 | |
| SCHEMBL3880185 | 0.75 | RXRA (0.64) | RXRATDP1ALDH1A1MAPK1SSTR5 | |
| SCHEMBL27858945 | 0.74 | TSHR (0.45) | RXRAALDH1A1KDM4ETSHR | |
| SCHEMBL6559892 | 0.74 | RXRA (0.49) | RXRATDP1ALDH1A1MAPK1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289547-A1 | Vaccine for treatment and prevention of herpes simplex virus infection | Antigenics Inc. (US) | 2011-03-02 | — | — | EP | disclosed |