SCHEMBL6489983

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10822265	0.87	RXRA (0.48)	RXRATDP1ALDH1A1MAPK1SSTR5
	SCHEMBL2812534	0.80	RXRA (0.52)	RXRATDP1ALDH1A1MAPK1SSTR5
	SCHEMBL1506790	0.78	RXRA (0.50)	RXRATDP1ALDH1A1MAPK1SSTR5
	SCHEMBL15947248	0.74	TSHR (0.43)	RXRAALDH1A1MAPK1KDM4EMAPT
	SCHEMBL30195971	0.72	RXRA (0.64)	RXRATDP1ALDH1A1MAPK1SSTR5
	SCHEMBL3880185	0.72	RXRA (0.64)	RXRATDP1ALDH1A1MAPK1SSTR5
	SCHEMBL14898029	0.72	RXRA (0.50)	RXRATDP1ALDH1A1MAPK1RARA
	SCHEMBL6559892	0.71	RXRA (0.49)	RXRATDP1ALDH1A1MAPK1RARA
	SCHEMBL16742282	0.70	RARA (0.51)	RXRATDP1ALDH1A1MAPK1RARA
	SCHEMBL17224747	0.70	AKR1B1 (0.44)	ALDH1A1HPGDKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.