SCHEMBL15068205

SCHEMBL15068205

CS(=O)(=O)c1ccc(NCC2CC2)c(Br)c1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
ALDH3A1 P30838 1/20 0.56
BRD4 O60885 8/20 0.54
PTGER4 P35408 2/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
VCP P55072 2/20 0.41
PTGS2 P35354 2/20 0.40
LRRK2 Q5S007 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15068130 0.87 BRD4 (0.55) ALDH1A1ALDH3A1BRD4PTGER4CNR1
SCHEMBL15067799 0.87 BRD4 (0.53) BRD4PTGER4CA1CA2CA9
SCHEMBL15067148 0.85 BRD4 (0.51) ALDH1A1ALDH3A1BRD4PTGER4CNR1
SCHEMBL3398803 0.82 ALDH1A1 (0.56) ALDH1A1ALDH3A1BRD4PTGER4MEN1
SCHEMBL3369999 0.79 KMT2A (0.69) ALDH1A1ALDH3A1BRD4MEN1KMT2A
SCHEMBL3997149 0.76 ALDH1A1 (0.53) ALDH1A1ALDH3A1BRD4MEN1KMT2A
SCHEMBL3994829 0.74 ALDH1A1 (0.51) ALDH1A1ALDH3A1BRD4PTGER4MEN1
SCHEMBL15552916 0.74 ALDH1A1 (0.48) ALDH1A1ALDH3A1BRD4MEN1KMT2A
SCHEMBL15068117 0.74 BRD4 (0.44) ALDH1A1ALDH3A1BRD4MEN1KMT2A
SCHEMBL22718326 0.73 GHSR (0.49) ALDH1A1MEN1KMT2APTGS2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4134364-B1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RES INC (US) 2025-07-30 EP disclosed
US-20240182490-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2024-06-06 US disclosed
US-11884680-B2 Bromodomain inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2024-01-30 US disclosed
EP-4134364-A2 BROMODOMAIN INHIBITORS Celgene Quanticel Research, Inc. (US) 2023-02-15 EP disclosed
US-20220315601-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2022-10-06 US disclosed
EP-3640241-B1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RES INC (US) 2022-09-28 EP disclosed
CN-108558889-B Bromodomain inhibitors 赛尔基因昆蒂赛尔研究公司 2021-11-05 CN disclosed
US-10941160-B2 Bromodomain inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2021-03-09 US disclosed
US-20200148703-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2020-05-14 US disclosed
EP-3640241-A1 BROMODOMAIN INHIBITORS Celgene Quanticel Research, Inc. (US) 2020-04-22 EP disclosed
EP-3057586-A1 BROMODOMAIN INHIBITORS Celgene Quanticel Research, Inc. (US) 2016-08-24 EP disclosed
CN-105828820-A Bromodomain inhibitors 赛尔基因昆蒂赛尔研究公司 2016-08-03 CN disclosed
US-20160115134-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. 2016-04-28 US disclosed
US-9115114-B2 Bromodomain inhibitors Quanticel Pharmaceuticals, Inc. (US) 2015-08-25 US disclosed
US-20150183784-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. 2015-07-02 US disclosed
US-9034900-B2 Bromodomain inhibitors Quanticel Pharmaceuticals, Inc. (US) 2015-05-19 US disclosed
US-20150111885-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. 2015-04-23 US disclosed
WO-2015058160-A1 BROMODOMAIN INHIBITORS Quanticel Pharmaceuticals, Inc. (US) 2015-04-23 WO disclosed
EP-2797918-A1 BROMODOMAIN INHIBITORS AbbVie Inc. (US) 2014-11-05 EP disclosed
WO-2013097601-A1 BROMODOMAIN INHIBITORS ABBVIE INC. (US) 2013-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182490-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 ALDH1A1 3316/4885ALDH3A1 2590/4885BRD4 5/4885
US-20220315601-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 ALDH1A1 3316/4885ALDH3A1 2590/4885BRD4 5/4885
US-20150111885-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 ALDH1A1 3316/4885ALDH3A1 2590/4885BRD4 5/4885
US-10941160-B2 Bromodomain inhibitors BRD3, EP300, BRPF3 ALDH1A1 3316/4885ALDH3A1 2590/4885BRD4 5/4885
US-20150183784-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 ALDH1A1 3316/4885ALDH3A1 2590/4885BRD4 5/4885
US-20200148703-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 ALDH1A1 3316/4885ALDH3A1 2590/4885BRD4 5/4885
US-11884680-B2 Bromodomain inhibitors BRD3, EP300, BRPF3 ALDH1A1 3316/4885ALDH3A1 2590/4885BRD4 5/4885
US-20160115134-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 ALDH1A1 3316/4885ALDH3A1 2590/4885BRD4 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.