Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 5/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15051963 | 0.80 | PTGDR2 (0.56) | KDM4ECCR5PTGDR2RAB9AALDH1A1 | |
| SCHEMBL15052594 | 0.78 | PTGER1 (0.47) | KDM4ETDP1PTGER1PTGDR2CYP1A2 | |
| SCHEMBL15068508 | 0.75 | PTGER1 (0.36) | KDM4ETDP1PTGER1RAB9ACYP1A2 | |
| SCHEMBL15052158 | 0.74 | PTGER1 (0.49) | PTGER1CYP1A2 | |
| SCHEMBL19547233 | 0.74 | PTGER1 (0.49) | PTGER1CYP1A2 | |
| SCHEMBL20628804 | 0.74 | RAB9A (0.39) | KDM4ECCR5PTGDR2RAB9AALDH1A1 | |
| SCHEMBL20628900 | 0.74 | PTGER1 (0.37) | CCR5PTGER1PTGDR2RAB9AALDH1A1 | |
| SCHEMBL20629012 | 0.73 | AAK1 (0.45) | KDM4ETDP1RAB9AALDH1A1LMNA | |
| SCHEMBL15076270 | 0.72 | NR1H4 (0.42) | PTGER1PTGDR2 | |
| SCHEMBL15076187 | 0.72 | PTGDR2 (0.39) | KDM4ECCR5PTGDR2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794561-A2 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013096496-A2 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2013-06-27 | — | — | WO | disclosed |