SCHEMBL1506977

SCHEMBL1506977

COc1cc(C=O)c(OC)c2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.58
ERN1 O75460 7/20 0.51
ALDH1A1 P00352 7/20 0.50
KDM4E B2RXH2 3/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPK1 P28482 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PRKDC P78527 2/20 0.46
TLR2 O60603 1/20 0.43
TLR1 Q15399 1/20 0.43
TLR6 Q9Y2C9 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31346762 1.00 MCL1 (0.58) MCL1ERN1ALDH1A1KDM4ETSHR
SCHEMBL1002837 0.86 MCL1 (0.68) MCL1ERN1ALDH1A1KDM4ETSHR
SCHEMBL30855494 0.85 MCL1 (0.72) MCL1ERN1ALDH1A1KDM4ETSHR
SCHEMBL18517642 0.85 MCL1 (0.72) MCL1ERN1ALDH1A1KDM4ETSHR
SCHEMBL13080199 0.83 MCL1 (0.45) MCL1ERN1ALDH1A1KDM4EMAPK1
SCHEMBL13894553 0.82 ALDH1A1 (0.50) MCL1ERN1ALDH1A1KDM4ETSHR
SCHEMBL8563051 0.82 ALDH1A1 (0.48) MCL1ERN1ALDH1A1KDM4EMAPK1
SCHEMBL5950414 0.82 ALDH1A1 (0.50) MCL1ERN1ALDH1A1KDM4ETSHR
SCHEMBL485541 0.82 MCL1 (0.58) MCL1ERN1ALDH1A1KDM4ETSHR
SCHEMBL25254136 0.81 PRKDC (0.53) MCL1ERN1ALDH1A1KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115813893-A Application of naphthyl skeleton compound in preparing coronavirus 3CL protease inhibitor 陕西科技大学 2023-03-21 CN claimed
CN-115813893-A Application of naphthyl skeleton compound in preparing coronavirus 3CL protease inhibitor 陕西科技大学 2023-03-21 CN disclosed
US-11091452-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORPORATION (JP) 2021-08-17 US disclosed
US-20200283399-A1 METHOD OF PRODUCING POLYMERIZABLE COMPOUND, AND SOLUTION OF POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2020-09-10 US disclosed
CN-106146338-B Naphthaquinone derivative containing adamantyl, preparation method and application thereof 中国科学院上海药物研究所 2020-09-08 CN disclosed
US-20200048213-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2020-02-13 US disclosed
EP-3604289-A1 POLYMERIZABLE COMPOUND PRODUCTION METHOD AND POLYMERIZABLE COMPOUND SOLUTION Zeon Corporation (JP) 2020-02-05 EP disclosed
US-10173992-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORPORATION (JP) 2019-01-08 US disclosed
EP-2871192-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORP (JP) 2018-06-20 EP disclosed
EP-2203161-B1 QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF UNIV INDIANA RES & TECH CORP (US) 2018-05-09 EP disclosed
EP-0757629-B1 IMAGING MEDIUM AND PROCESS POLAROID CORP (US) 1999-01-20 EP disclosed
EP-0549366-B1 Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses SANKYO CO (JP) 1998-04-15 EP disclosed
US-5631118-A MULTILAYER ELEMENT WITH ACID GENERATING LAYER, ACID PRECURSOR, SENSITIZING DYE, ACID GENERATOR AND COLOR CHANGING LAYER POLAROID CORPORATION (US) 1997-05-20 US disclosed
EP-0757629-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1997-02-12 EP disclosed
WO-1995029068-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1995-11-02 WO disclosed
US-5441850-A Exposing medium to actinic radiation in specified wavelength so sensitizing dye decomposes superacid precursor, heating to decompose secondary acid generator, mixing acid generating and color change layers to form image, providing base to restore POLAROID CORPORATION (US) 1995-08-15 US disclosed
EP-0549365-B1 Thiazolidine compounds, their preparation and their therapeutic uses SANKYO CO (JP) 1995-08-09 EP disclosed
US-5338855-A Treating diabetes or hyperlipemia SANKYO COMPANY, LIMITED (JP) 1994-08-16 US disclosed
EP-0549366-A1 Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses Sankyo Company Limited (JP) 1993-06-30 EP disclosed
EP-0549365-A1 Thiazolidine compounds, their preparation and their therapeutic uses Sankyo Company Limited (JP) 1993-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10173992-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound PYM1, C5, C1S MCL1 2664/4885ERN1 3193/4885ALDH1A1 987/4885
US-20200048213-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND PDE8A, MAPT, PLK4 MCL1 4198/4885ERN1 1196/4885ALDH1A1 3468/4885
US-11091452-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound PDE8A, MAPT, PLK4 MCL1 4198/4885ERN1 1196/4885ALDH1A1 3468/4885
US-20200283399-A1 METHOD OF PRODUCING POLYMERIZABLE COMPOUND, AND SOLUTION OF POLYMERIZABLE COMPOUND PDE8A, ADCY6, TKFC MCL1 3032/4885ERN1 1631/4885ALDH1A1 2498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.