Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 5/20 | 0.42 |
| ▸ | ATP4B | P51164 | 5/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069838 | 0.78 | ALDH1A1 (0.38) | GRM1PTK2ALDH1A1LMNATP53 | |
| SCHEMBL19100879 | 0.74 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL17208676 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL16475120 | 0.72 | KDM4E (0.33) | ALDH1A1KDM4E | |
| SCHEMBL19657260 | 0.70 | — | — | |
| SCHEMBL16923796 | 0.69 | HTR6 (0.48) | ALDH1A1LMNA | |
| SCHEMBL16923795 | 0.69 | PIK3C3 (0.37) | — | |
| SCHEMBL1239659 | 0.68 | ALDH1A1 (0.54) | ALDH1A1CYP1A2KDM4E | |
| SCHEMBL28353289 | 0.67 | PIK3CA (0.36) | ALDH1A1KDM4E | |
| SCHEMBL31073850 | 0.67 | KMT2A (0.38) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013097052-A1 | BROMODOMAIN INHIBITORS | ABBOTT LABORATORIES (US) | 2013-07-04 | — | — | WO | disclosed |