Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069840 | 0.78 | ATP4A (0.42) | ALDH1A1LMNAPTK2GRM1TP53 | |
| SCHEMBL19100879 | 0.76 | ALDH1A1 (0.31) | ALDH1A1MAPT | |
| SCHEMBL15069582 | 0.76 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1HTTKMT2A | |
| SCHEMBL17208676 | 0.75 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL16475120 | 0.74 | KDM4E (0.33) | ALDH1A1MAPTKMT2A | |
| SCHEMBL19657260 | 0.71 | — | — | |
| SCHEMBL16923795 | 0.70 | PIK3C3 (0.37) | SMN1; SMN2HTT | |
| SCHEMBL15483481 | 0.68 | L3MBTL1 (0.39) | ALDH1A1RAB9ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL30574599 | 0.68 | ABL1 (0.38) | ALDH1A1LMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL28349658 | 0.68 | ABL1 (0.38) | ALDH1A1LMNASMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013097052-A1 | BROMODOMAIN INHIBITORS | ABBOTT LABORATORIES (US) | 2013-07-04 | — | — | WO | disclosed |