Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070911 | 0.92 | CYP4F2 (0.47) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL27681347 | 0.90 | CYP4F2 (0.54) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL16150101 | 0.86 | CYP4F2 (0.50) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL10023943 | 0.86 | CYP4F2 (0.50) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL23132525 | 0.85 | CYP4F2 (0.42) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL1361264 | 0.82 | CYP4F2 (0.44) | CYP4F2CYP4A11PKMTHRBHTT | |
| Propylene Glycol SCHEMBL27727755 | 0.82 | CYP4F2 (0.49) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL21703602 | 0.81 | CYP4F2 (0.63) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL15074624 | 0.80 | MEN1 (0.42) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL3772643 | 0.80 | CYP4F2 (0.43) | CYP4F2CYP4A11PKMTHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2018-03-08 | — | — | US | disclosed |
| US-9815765-B2 | Ruthenium polymerisation catalysts | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2017-11-14 | — | — | US | disclosed |
| US-9233994-B2 | Ruthenium complexes for use in olefin metathesis | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2016-01-12 | — | — | US | disclosed |
| US-20140228563-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2014-08-14 | — | — | US | disclosed |
| US-20130165649-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | RRP12, PCBP1, PARG | CYP4F2 1707/4885CYP4A11 3716/4885PKM 273/4885 |
| US-20130165649-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | OSBP, CYCS, OSBPL3 | CYP4F2 341/4885CYP4A11 2489/4885PKM 3045/4885 |
| US-20140228563-A1 | RUTHENIUM POLYMERISATION CATALYSTS | RRP12, PCBP1, PARG | CYP4F2 1707/4885CYP4A11 3716/4885PKM 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.