Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.63 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.63 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1361264 | 0.82 | CYP4F2 (0.44) | CYP4F2CYP4A11PKMKDM4ETHRB | |
| SCHEMBL4906188 | 0.81 | CYP4F2 (0.74) | CYP4F2CYP4A11PKMKDM4ETHRB | |
| SCHEMBL27681347 | 0.81 | CYP4F2 (0.54) | CYP4F2CYP4A11PKMKDM4ETHRB | |
| SCHEMBL15070913 | 0.81 | CYP4F2 (0.54) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL10023943 | 0.79 | CYP4F2 (0.50) | CYP4F2CYP4A11PKMKDM4ETHRB | |
| SCHEMBL16150101 | 0.79 | CYP4F2 (0.50) | CYP4F2CYP4A11PKMKDM4ETHRB | |
| SCHEMBL23132525 | 0.78 | CYP4F2 (0.42) | CYP4F2CYP4A11PKMKDM4ETHRB | |
| SCHEMBL23309172 | 0.78 | CYP4F2 (1.00) | CYP4F2CYP4A11PKMKDM4ETHRB | |
| SCHEMBL20988221 | 0.77 | CYP4F2 (0.46) | CYP4F2CYP4A11PKMKDM4ETHRB | |
| SCHEMBL21703605 | 0.77 | CYP4F2 (0.46) | CYP4F2CYP4A11PKMKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3480190-B1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | CALIFORNIA INST OF TECHN (US) | 2023-01-04 | — | — | EP | disclosed |
| US-10745354-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-08-18 | — | — | US | disclosed |
| US-20200048201-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048201-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | LSS, COASY, ADH1A | CYP4F2 815/4885CYP4A11 116/4885PKM 3897/4885 |
| US-10745354-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | LSS, COASY, ADH1A | CYP4F2 815/4885CYP4A11 116/4885PKM 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.