Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | GLA | P06280 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.59 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.59 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.59 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15050028 | 1.00 | KDM4E (0.67) | KDM4EKMT2AALDH1A1HPGDGLA | |
| SCHEMBL2594783 | 0.92 | KDM4E (0.63) | KDM4EKMT2AALDH1A1HPGDGLA | |
| SCHEMBL12180841 | 0.88 | RAF1 (0.68) | KDM4EKMT2AALDH1A1HPGDGLA | |
| SCHEMBL2593317 | 0.85 | KDM4E (0.91) | KDM4EKMT2AALDH1A1HPGDGLA | |
| SCHEMBL15071001 | 0.84 | MAPK14 (0.63) | KDM4EKMT2AALDH1A1HPGDGLA | |
| SCHEMBL29103864 | 0.80 | KDM4E (0.83) | KDM4EKMT2AALDH1A1HPGDGLA | |
| SCHEMBL29642733 | 0.79 | KDM4E (1.00) | KDM4EKMT2AALDH1A1HPGDGLA | |
| SCHEMBL16497610 | 0.79 | MAPK14 (0.81) | KDM4EKMT2AALDH1A1HPGDGLA | |
| SCHEMBL12561695 | 0.79 | KDM4E (0.80) | KDM4EKMT2AALDH1A1HPGDGLA | |
| SCHEMBL12561724 | 0.78 | KDM4E (0.70) | KDM4EKMT2AALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165489-A1 | Small Molecule Modulators of HIV-1 Capsid Stability and Methods Thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165489-A1 | Small Molecule Modulators of HIV-1 Capsid Stability and Methods Thereof | ZC3HAV1, MAVS, HAVCR2 | KDM4E 1542/4885KMT2A 3224/4885ALDH1A1 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.