Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23354976 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4ELMNACYP2C19TSHR | |
| SCHEMBL15069965 | 0.77 | SMN1; SMN2 (0.36) | SMN1; SMN2KDM4ELMNACYP2C19TSHR | |
| SCHEMBL13414741 | 0.74 | KDM4E (0.34) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL15071287 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4ELMNACYP2C19TSHR | |
| SCHEMBL3079790 | 0.69 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4ELMNACYP2C19TSHR | |
| SCHEMBL7436133 | 0.67 | — | — | |
| SCHEMBL5449273 | 0.67 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4ELMNACYP2C19TSHR | |
| SCHEMBL10263814 | 0.65 | CYP11B1 (0.46) | SMN1; SMN2KDM4ELMNATSHR | |
| SCHEMBL25051610 | 0.64 | HSD17B10 (0.39) | SMN1; SMN2KDM4ELMNACYP2C19TSHR | |
| SCHEMBL13629764 | 0.64 | KDM4E (0.34) | KDM4ELMNACYP2C19TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557927-B2 | Comb-shaped graft copolymers and methods of manufacturing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-10-15 | — | — | US | disclosed |
| US-20130165592-A1 | COMB-SHAPED GRAFT COPOLYMERS AND METHODS OF MANUFACTURING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-06-27 | — | — | US | disclosed |