Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13629764 | 0.87 | KDM4E (0.34) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL15071286 | 0.85 | — | — | |
| SCHEMBL3676473 | 0.80 | KDM4E (0.34) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL3676476 | 0.78 | KDM4E (0.33) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL15069993 | 0.75 | KDM4E (0.31) | KDM4ELMNACYP2C19 | |
| SCHEMBL18217981 | 0.75 | KDM4E (0.31) | KDM4ELMNACYP2C19 | |
| SCHEMBL15071289 | 0.74 | SMN1; SMN2 (0.39) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL23354654 | 0.72 | KDM4E (0.33) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL15069995 | 0.69 | KDM4E (0.31) | KDM4ELMNACYP2C19 | |
| SCHEMBL15314183 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557927-B2 | Comb-shaped graft copolymers and methods of manufacturing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-10-15 | — | — | US | disclosed |
| US-8513417-B2 | Method for synthesis of nitroxyl radical | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-20130165592-A1 | COMB-SHAPED GRAFT COPOLYMERS AND METHODS OF MANUFACTURING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-06-27 | — | — | US | disclosed |
| US-20100076190-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076190-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | NOX4, TXN2, TXNRD2 | KDM4E 984/4885LMNA 2893/4885CYP2C19 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.