Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995460 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4ELMNACYP2C19CYP11B1 | |
| SCHEMBL15070002 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2 | |
| SCHEMBL19919573 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2CRBN | |
| SCHEMBL5328437 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNA | |
| SCHEMBL21042654 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2CRBNCTSKKDM4ELMNA | |
| SCHEMBL578932 | 0.72 | GAA (0.35) | CRBNCYP2C19TSHR | |
| SCHEMBL248285 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL11333509 | 0.70 | GAA (0.34) | CYP2C19TSHR | |
| Iodide SCHEMBL6292630 | 0.70 | GAA (0.34) | CYP2C19TSHR | |
| SCHEMBL9717101 | 0.70 | GAA (0.34) | CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070256352-A1 | Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith | WOOD MERVIN G | 2007-11-08 | — | — | US | claimed |
| US-8557927-B2 | Comb-shaped graft copolymers and methods of manufacturing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-10-15 | — | — | US | disclosed |
| US-20130165592-A1 | COMB-SHAPED GRAFT COPOLYMERS AND METHODS OF MANUFACTURING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-06-27 | — | — | US | disclosed |
| US-20070256352-A1 | Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith | WOOD MERVIN G | 2007-11-08 | — | — | US | disclosed |
| US-4202816-A | ENOL-PIPERIDINE METAL COMPLEXES | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070256352-A1 | Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith | CRY1, GPX4, CAND1 | SMN1; SMN2 1627/4885CRBN 470/4885CTSK 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.