SCHEMBL15071422

SCHEMBL15071422

Cc1ccc(C(C(F)(F)F)C(F)(F)F)cc1C

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.35
TRPA1 O75762 1/20 0.34
PTGS1 P23219 1/20 0.34
CACNA1C Q13936 1/20 0.34
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 2/20 0.30
TSHR P16473 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13703416 0.82 ESR1 (0.48) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL16736878 0.81 TRPA1 (0.59) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL28779026 0.81 ALDH1A1 (0.45) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL3277990 0.81 CYP3A4 (0.45) ALDH1A1ESR1ESR2TP53TDP1
SCHEMBL23983161 0.80 LMNA (0.39) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL25767054 0.80 LMNA (0.39) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL28490610 0.80 LMNA (0.39) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL19828916 0.78 ALDH1A1 (0.33) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL7647445 0.74 ESR1 (0.46) ESR1ESR2
SCHEMBL9570827 0.74 TP53 (0.31) ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9688815-B2 Method for producing polyimide precursor and method for producing polyimide RICOH COMPANY, LTD. (JP) 2017-06-27 US disclosed
US-20160122474-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICHO COMPANY, LTD. (JP) 2016-05-05 US disclosed
US-9209444-B2 Polymide blend nanofiber and its use in battery separator JIANGXI ADVANCE NANOFIBER S&T CO., LTD. (CN) 2015-12-08 US disclosed
US-20130164629-A1 POLYMIDE BLEND NANOFIBER AND ITS USE IN BATTERY SEPARATOR JIANGXI ADVANCE NANOFIBER S&T CO., LTD. (CN) 2013-06-27 US disclosed