Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10520281 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1538972 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1538821 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28671040 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL396600 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1854489 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11435761 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6563754 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28410687 | 0.97 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL1232118 | 0.93 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 836 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924601-B | Copolymer, preparation method thereof, vulcanized rubber and application thereof | 中国石油化工股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119192500-A | Ethylene-isoprene polymer, preparation method thereof and vulcanized rubber | 中国石油化工股份有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-119192499-A | Ethylene-butadiene polymer, process for producing the same, and vulcanized rubber | 中国石油化工股份有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-119192498-A | Ethylene-butadiene polymer, process for producing the same, and vulcanized rubber | 中国石油化工股份有限公司 | 2024-12-27 | — | — | CN | claimed |
| WO-2024088247-A1 | COPOLYMER, PREPARATION METHOD THEREFOR, VULCANIZED RUBBER AND USE THEREOF | 中国石油化工股份有限公司 | 2024-05-02 | — | — | WO | claimed |
| CN-117924601-A | Copolymer, preparation method thereof, vulcanized rubber and application thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| US-11427700-B2 | Method of manufacturing rubber composition | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2022-08-30 | — | — | US | claimed |
| CN-106397648-B | The poly- conjugated diolefin of high 3,4- of the side arm with unsaturated group or functional group and its their preparation method | 中国科学院长春应用化学研究所 | 2019-03-05 | — | — | CN | claimed |
| US-9856337-B2 | Polymerization catalysts | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-01-02 | — | — | US | claimed |
| US-20170275402-A1 | POLYMERIZATION CATALYSTS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2017-09-28 | — | — | US | claimed |
| US-7468417-B2 | Method of preparing cyclic olefin copolymer having controlled gel contents | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2008-12-23 | — | — | US | claimed |
| US-20070060730-A1 | METHOD OF PREPARING CYCLIC OLEFIN COPOLYMER HAVING CONTROLLED GEL CONTENTS | KOREA KUMHO PETROCHEMICAL CO., LTD./NEW KOREA INTE (KR) | 2007-03-15 | — | — | US | claimed |
| US-6093674-A | CATALYST FOR GAS PHASE POLYMERIZATION OF CONJUGATED DIENES WITH ELEVATED CONTENT OF LATERAL DOUBLE BONDS | BAYER AG (DE) | 2000-07-25 | — | — | US | claimed |
| US-3960765-A | REDUCING TITANIUM TETRACHLORIDE WITH AN ORGANOALUMINUM COMPOUND, COMPLEXING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-06-01 | — | — | US | claimed |
| US-20260139129-A1 | Polyethylene Resin Composition | SONG, Christine Jisoo (KR) | 2026-05-21 | — | — | US | disclosed |
| EP-3969490-B1 | MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND TIRE COMPONENTS | BRIDGESTONE CORP (JP) | 2026-03-25 | — | — | EP | disclosed |
| US-20250389555-A1 | MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2025-12-25 | — | — | US | disclosed |
| US-4052473-A | OF ISOPRENE, NICKEL-ALKYLAMUMIN HALIDE CONTAINING CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-04 | — | — | US | disclosed |
| US-4031300-A | High molecular weight, high unsaturation isobutylene-cyclopentadiene copolymers | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1977-06-21 | — | — | US | disclosed |
| US-3960765-A | REDUCING TITANIUM TETRACHLORIDE WITH AN ORGANOALUMINUM COMPOUND, COMPLEXING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260139129-A1 | Polyethylene Resin Composition | MACF1, LBR, SMCHD1 | TSHR 1067/4885THRB 3202/4885DNM1 1776/4885 |
| US-20170275402-A1 | POLYMERIZATION CATALYSTS | SIK2, SIK3, SGK2 | TSHR 4821/4885THRB 4662/4885DNM1 2237/4885 |
| US-20250389555-A1 | MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS | MALT1, INO80C, RTCB | TSHR 1694/4885THRB 529/4885DNM1 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.