SCHEMBL15072039

SCHEMBL15072039

CC[C@H]1OC[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
LMNA P02545 1/20 0.38
SPHK2 Q9NRA0 7/20 0.37
SPHK1 Q9NYA1 6/20 0.37
GBA1 P04062 3/20 0.37
GANAB Q14697 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
LGALS3 P17931 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12838262 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL15623379 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL11083697 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL14410884 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL19782035 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL23988570 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL13082871 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL17779781 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL21095378 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL19782036 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9879048-B2 Isolation, identification, and uses of antifungal compounds UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2018-01-30 US disclosed
WO-2013096697-A2 ISOLATION, IDENTIFICATION, AND USED OF ANTIFUNGAL COMPOUNDS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2013-06-27 WO disclosed