SCHEMBL19782035

SCHEMBL19782035

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nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
LMNA P02545 1/20 0.38
SPHK2 Q9NRA0 7/20 0.37
SPHK1 Q9NYA1 6/20 0.37
GBA1 P04062 3/20 0.37
GANAB Q14697 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
LGALS3 P17931 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15072039 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL12838262 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL15623379 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL11083697 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL14410884 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL23988570 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL13082871 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL17779781 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL21095378 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL19782036 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365610-A1 Aryl Glucoside Derivative SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-11-16 US disclosed
US-20180016291-A1 Rebaudioside Analogs PEPSICO, INC. 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180016291-A1 Rebaudioside Analogs SLC5A1, TAS1R1, FBP1 THRB 3312/4885LMNA 4015/4885SPHK2 1500/4885
US-20230365610-A1 Aryl Glucoside Derivative SLC5A1, SLC5A2, SLC10A1 THRB 1608/4885LMNA 3998/4885SPHK2 2339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.