SCHEMBL12838262

SCHEMBL12838262

CCC1OCC(O)C(O)C1O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
LMNA P02545 1/20 0.38
SPHK2 Q9NRA0 7/20 0.37
SPHK1 Q9NYA1 6/20 0.37
GBA1 P04062 3/20 0.37
GANAB Q14697 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
LGALS3 P17931 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15072039 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL15623379 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL11083697 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL14410884 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL19782035 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL23988570 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL13082871 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL17779781 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL21095378 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1
SCHEMBL19782036 1.00 THRB (0.38) THRBLMNASPHK2SPHK1GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230098432-A1 SYNTHESIS OF GLYCOSYL FLUORIDES CARBOCODE S A (PT) 2023-03-30 US disclosed
US-20230094369-A1 SYNTHESIS OF GLYCOSYLATED SPHINGOID BASES OF INTEREST OR ANALOGUES THEREOF CARBOCODE S A (PT) 2023-03-30 US disclosed
US-11540539-B2 Reduced sodium food products GENERAL MILLS, INC. (US) 2023-01-03 US disclosed
EP-3054958-B1 NEW PRADIMICIN DERIVATIVES FOR THE TREATMENT OF DISEASES CAUSED BY KINETOPLASTIDS UNIV LEUVEN KATH (BE) 2020-06-03 EP disclosed
US-20170172920-A1 LIPOSOMES WITH GINSENOSIDE AS MEMBRANE MATERIAL AND PREPARATIONS AND USE THEREOF Xiamen Ginposome Pharmaceutical Co., Ltd. (CN) 2017-06-22 US disclosed
US-20160279248-A1 EXTRACELLULAR TARGETED DRUG CONJUGATES CENTROSE, LLC 2016-09-29 US disclosed
US-9364554-B2 Extracellular targeted drug conjugates CENTROSE LLC (US) 2016-06-14 US disclosed
US-20160045418-A1 HAIR CARE SHAMPOO HENKEL AG & CO. KGAA (DE) 2016-02-18 US disclosed
WO-2015143185-A1 AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME AMYDIS DIAGNOSTICS (US) 2015-09-24 WO disclosed
US-20140128309-A1 CONDITIONING COSMETIC CLEANING AGENT HAVING IMPROVED FOAMING PROPERTIES HENKEL AG & CO. KGAA (DE) 2014-05-08 US disclosed
US-8470980-B2 Extracellular targeted drug conjugates CENTROSE, LLC (US) 2013-06-25 US disclosed
US-20110064752-A1 EXTRACELLULAR TARGETED DRUG CONJUGATES CENTROSE, LLC (US) 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110064752-A1 EXTRACELLULAR TARGETED DRUG CONJUGATES FCGR2A, ENGASE, FCER2 THRB 1602/4885LMNA 1783/4885SPHK2 3589/4885
US-20230098432-A1 SYNTHESIS OF GLYCOSYL FLUORIDES MAN2B1, GBA1, FUCA1 THRB 752/4885LMNA 2492/4885SPHK2 1397/4885
US-20160045418-A1 HAIR CARE SHAMPOO CD44, CUTA, ALG1 THRB 3196/4885LMNA 1684/4885SPHK2 422/4885
US-20170172920-A1 LIPOSOMES WITH GINSENOSIDE AS MEMBRANE MATERIAL AND PREPARATIONS AND USE THEREOF SGMS1, LIPA, SGMS2 THRB 4857/4885LMNA 320/4885SPHK2 350/4885
US-20160279248-A1 EXTRACELLULAR TARGETED DRUG CONJUGATES FCGR2A, ENGASE, FCER2 THRB 1602/4885LMNA 1783/4885SPHK2 3589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.