Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | CDC25A | P30304 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.52 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627646 | 0.78 | PTPN1 (0.70) | CDC25BMAPTMAPK1MEN1KMT2A | |
| SCHEMBL30038980 | 0.78 | PTPN1 (0.70) | CDC25BMAPTMAPK1MEN1KMT2A | |
| SCHEMBL5810766 | 0.78 | PTPN1 (0.59) | CDC25BMAPTMAPK1MEN1KMT2A | |
| SCHEMBL9628284 | 0.76 | PTPN1 (0.52) | CDC25BMAPTMAPK1MEN1KMT2A | |
| SCHEMBL5817375 | 0.75 | PTPN1 (0.55) | CDC25BMAPTMAPK1MEN1KMT2A | |
| SCHEMBL7913517 | 0.75 | BACE1 (0.50) | CDC25BMAPTMAPK1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28549609 | 0.75 | PTPN1 (0.50) | CDC25BMAPTMAPK1MEN1KMT2A | |
| SCHEMBL28514269 | 0.74 | CDC25B (0.56) | CDC25BMAPTMAPK1MEN1KMT2A | |
| SCHEMBL125298 | 0.73 | CDC25B (0.56) | CDC25BMAPTMAPK1MEN1KMT2A | |
| SCHEMBL10446585 | 0.72 | PTPN1 (0.47) | CDC25BMAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257515-B1 | 1,4-NAPHTHOQUINONE DERIVATIVES AND THERAPEUTIC USE THEREOF | CENTRE NAT RECH SCIENT (FR) | 2017-05-17 | — | — | EP | disclosed |
| US-9090549-B2 | 1,4-naphthoquinones derivatives and therapeutic use thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20110059972-A1 | 1,4-NAPHTHOQUINONES DERIVATIVES AND THERAPEUTIC USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-03-10 | — | — | US | disclosed |
| EP-2257515-A1 | 1,4-NAPHTHOQUINONE DERIVATIVES AND THERAPEUTIC USE THEREOF | Centre National de la Recherche Scientifique (FR) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009118327-A1 | 1,4-NAPHTHOQUINONE DERIVATIVES AND THERAPEUTIC USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059972-A1 | 1,4-NAPHTHOQUINONES DERIVATIVES AND THERAPEUTIC USE THEREOF | NQO1, NDUFV2, RECQL | CDC25B 576/4885MAPT 2505/4885MAPK1 3395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.