SCHEMBL125298

SCHEMBL125298

O=C1C=C(F)C(=O)c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 5/20 0.56
MAPT P10636 5/20 0.56
MAPK1 P28482 5/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
LMNA P02545 4/20 0.56
ALDH1A1 P00352 4/20 0.56
IDO1 P14902 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
CDC25A P30304 3/20 0.56
MAOA P21397 3/20 0.56
HPGD P15428 3/20 0.56
PLIN1 O60240 2/20 0.56
BLM P54132 2/20 0.56
PLIN5 Q00G26 2/20 0.56
ABHD5 Q8WTS1 2/20 0.56
MAOB P27338 2/20 0.56
SNCA P37840 2/20 0.56
CYP3A4 P08684 2/20 0.56
GAA P10253 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6555840 0.75 BACE1 (0.75) CDC25BMAPTMAPK1MEN1KMT2A
SCHEMBL4657279 0.73 MAPT (0.58) CDC25BMAPTMAPK1MEN1KMT2A
SCHEMBL1507238 0.73 CDC25B (0.52) CDC25BMAPTMAPK1MEN1KMT2A
Menadione SCHEMBL19356853 0.71 MAPT (1.00) CDC25BMAPTMAPK1MEN1KMT2A
Lawsone SCHEMBL6849999 0.71 MAPT (0.68) CDC25BMAPTMAPK1MEN1KMT2A
SCHEMBL25358615 0.71 MAPT (0.56) CDC25BMAPTMAPK1MEN1KMT2A
SCHEMBL13769114 0.71 CDC25B (0.56) CDC25BMAPTMAPK1MEN1KMT2A
Menadione SCHEMBL1364028 0.71 MAPT (1.00) CDC25BMAPTMAPK1MEN1KMT2A
SCHEMBL14763777 0.71 MAPT (0.56) CDC25BMAPTMAPK1MEN1KMT2A
Menadione SCHEMBL25970 0.71 MAPT (1.00) CDC25BMAPTMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767308-B2 Method of stabilizing perfluorodioxolane compound, perfluorodioxolane compound-containing composition and method of producing perfluorodioxolane compound polymer TOSOH CORPORATION (JP) 2023-09-26 US disclosed
US-11767308-B2 Method of stabilizing perfluorodioxolane compound, perfluorodioxolane compound-containing composition and method of producing perfluorodioxolane compound polymer TOSOH CORPORATION (JP) 2023-09-26 US disclosed
US-9032876-B2 Lithographic printing plate precursor, lithographic printing plate platemaking method, and polymerizable monomer FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
CN-102227316-B Lithographic printing plate precursor, lithographic printing plate making method and polymerizable monomer FUJI PHOTO FILM CO LTD 2014-04-02 CN disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
EP-2100731-B1 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORP (JP) 2012-06-20 EP disclosed
US-8187791-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-8142983-B2 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
EP-2082875-B1 Lithographic printing plate precursor and plate making method using the precursor FUJIFILM CORP (JP) 2012-03-07 EP disclosed
EP-2165829-B1 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORP (JP) 2011-11-16 EP disclosed
US-20090233229-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed
US-20090233222-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed
EP-2100731-A2 Lithographic printing plate precursor and method of lithographic printing Fujifilm Corporation (JP) 2009-09-16 EP disclosed
EP-2082875-A1 Lithographic printing plate precursor and plate making method thereof FUJIFILM Corporation (JP) 2009-07-29 EP disclosed
EP-0244309-B1 RODENTICIDAL COMPOSITIONS CONTAINING 1,4-NAPHTHOQUINONE DERIVATIVES DUKE UNIVERSITY (US) 1993-02-03 EP disclosed
EP-0170190-B1 METHOD FOR PRODUCTION OF FLUORINATED QUINONES Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1989-12-06 EP disclosed
US-4734282-A Rodenticidal compositions containing 1,4-naphthoquinone derivatives DUKE UNIVERSITY (US) 1988-03-29 US disclosed
EP-0244309-A2 Rodenticidal compositions containing 1,4-naphthoquinone derivatives DUKE UNIVERSITY (US) 1987-11-04 EP disclosed
US-4689179-A FLUORINATION OF CHLORINATED ANHYDRIDES OR QUINONES; CROWN ETHER CATALYST, PHASE TRANSFER NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1987-08-25 US disclosed
EP-0170190-A2 Method for production of fluorinated quinones Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1986-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767308-B2 Method of stabilizing perfluorodioxolane compound, perfluorodioxolane compound-containing composition and method of producing perfluorodioxolane compound polymer PFAS, PFN1, PFKFB1 CDC25B 1328/4885MAPT 2077/4885MAPK1 1648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.