Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18655565 | 0.86 | TDP1 (0.35) | PRKCA | |
| SCHEMBL638234 | 0.82 | PRKCA (0.35) | PRKCA | |
| SCHEMBL14566479 | 0.81 | MEN1 (0.35) | PRKCAALDH1A1 | |
| SCHEMBL18655554 | 0.81 | PRKCA (0.34) | PRKCA | |
| SCHEMBL18655549 | 0.81 | PRKCA (0.34) | PRKCA | |
| SCHEMBL18655539 | 0.81 | PRKCA (0.34) | PRKCA | |
| SCHEMBL14566524 | 0.80 | PRKCA (0.33) | PRKCA | |
| SCHEMBL8211801 | 0.79 | PRKCA (0.45) | PRKCA | |
| SCHEMBL14632084 | 0.79 | TSHR (0.41) | ALDH1A1 | |
| SCHEMBL2957024 | 0.79 | PRKCA (0.36) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190875-A1 | SPIROINDOLINE DERIVATIVE, AND PREPARATION METHOD AND MEDICAL USE THEREOF | CHANGCHUN GENESCIENCE PHARMACEUTICAL CO., LTD. (CN) | 2024-06-13 | — | — | US | disclosed |
| EP-4282867-A1 | INDOLINE-CONTAINING SPIRO DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2023-11-29 | — | — | EP | disclosed |
| CN-105801489-B | Cycloalkyl-substituted imidazole derivatives | 第一三共株式会社 | 2019-12-10 | — | — | CN | disclosed |
| EP-2548871-B1 | CYCLOALKYL-SUBSTITUTED IMIDAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-9340531-B2 | Cycloalkyl-substituted imidazole derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-05-17 | — | — | US | disclosed |
| US-9340531-B2 | Cycloalkyl-substituted imidazole derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-05-17 | — | — | US | disclosed |
| US-9340531-B2 | Cycloalkyl-substituted imidazole derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-05-17 | — | — | US | disclosed |
| US-20140178349-A1 | Cycloalkyl-Substituted Imidazole Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-06-26 | — | — | US | disclosed |
| US-8609710-B2 | Cycloalkyl-substituted imidazole derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-12-17 | — | — | US | disclosed |
| US-20130230501-A9 | Cycloalkyl-Substituted Imidazole Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-09-05 | — | — | US | disclosed |
| US-20130230501-A9 | Cycloalkyl-Substituted Imidazole Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-09-05 | — | — | US | disclosed |
| US-20130230501-A9 | Cycloalkyl-Substituted Imidazole Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-09-05 | — | — | US | disclosed |
| US-20130022587-A1 | Cycloalkyl-Substituted Imidazole Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-24 | — | — | US | disclosed |
| US-20130022587-A1 | Cycloalkyl-Substituted Imidazole Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-24 | — | — | US | disclosed |
| US-20130022587-A1 | Cycloalkyl-Substituted Imidazole Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-24 | — | — | US | disclosed |
| EP-2548871-A1 | CYCLOALKYL-SUBSTITUTED IMIDAZOLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-23 | — | — | EP | disclosed |
| EP-2292590-A2 | Prodrugs of 9-aminomethyl tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-03-09 | — | — | EP | disclosed |
| US-20100249076-A1 | PRODRUGS OF 9-AMINOMETHYL TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| US-20060287283-A1 | Prodrugs of 9-aminomethyl tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2006-12-21 | — | — | US | disclosed |
| US-20050137174-A1 | Prodrugs of 9-aminomethyl tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130022587-A1 | Cycloalkyl-Substituted Imidazole Derivative | F7, F12, TFPI | PRKCA 2324/4885ALDH1A1 4432/4885 |
| US-20240190875-A1 | SPIROINDOLINE DERIVATIVE, AND PREPARATION METHOD AND MEDICAL USE THEREOF | GHSR, GHRHR, NR3C2 | PRKCA 4213/4885ALDH1A1 1759/4885 |
| US-20100249076-A1 | PRODRUGS OF 9-AMINOMETHYL TETRACYCLINE COMPOUNDS | TET3, TET1, TPMT | PRKCA 4113/4885ALDH1A1 3508/4885 |
| US-20050137174-A1 | Prodrugs of 9-aminomethyl tetracycline compounds | TET3, TET1, TPMT | PRKCA 4113/4885ALDH1A1 3508/4885 |
| US-20130230501-A9 | Cycloalkyl-Substituted Imidazole Derivative | F7, F12, TFPI | PRKCA 2324/4885ALDH1A1 4432/4885 |
| US-20060287283-A1 | Prodrugs of 9-aminomethyl tetracycline compounds | TET3, TET1, TPMT | PRKCA 4113/4885ALDH1A1 3508/4885 |
| US-20140178349-A1 | Cycloalkyl-Substituted Imidazole Derivative | F7, F12, TFPI | PRKCA 2324/4885ALDH1A1 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.