Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 8/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400997 | 0.86 | KCNJ1 (0.51) | KCNJ1KCNH2HRH3TSHRALDH1A1 | |
| SCHEMBL16425199 | 0.76 | MAPT (0.60) | KCNJ1KCNH2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7758215 | 0.70 | TSHR (0.58) | KCNJ1KCNH2HRH3TSHRALDH1A1 | |
| SCHEMBL30484396 | 0.70 | ALDH1A1 (0.68) | KCNJ1KCNH2HRH3ALDH1A1MAPT | |
| SCHEMBL4404789 | 0.70 | ALDH1A1 (0.65) | KCNJ1KCNH2HRH3ALDH1A1MAPT | |
| SCHEMBL15074911 | 0.70 | TSHR (0.61) | KCNJ1KCNH2HRH3TSHRALDH1A1 | |
| SCHEMBL7999122 | 0.69 | TSHR (0.66) | KCNJ1KCNH2HRH3TSHRALDH1A1 | |
| SCHEMBL5396090 | 0.69 | TSHR (0.56) | KCNJ1KCNH2HRH3TSHRALDH1A1 | |
| SCHEMBL1628272 | 0.69 | TSHR (0.56) | KCNJ1KCNH2HRH3TSHRALDH1A1 | |
| SCHEMBL11729107 | 0.69 | TSHR (0.51) | KCNJ1KCNH2HRH3TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013093720-A2 | ANTI-DIABETIC COMPOUNDS | PFIZER INC. (US) | 2013-06-27 | — | — | WO | disclosed |