Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400997 | 0.87 | KCNJ1 (0.51) | MAPTSMN1; SMN2RECQLKCNJ1KCNH2 | |
| SCHEMBL16425193 | 0.78 | ALDH1A1 (0.45) | MAPTSMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL6535800 | 0.78 | ALDH1A1 (0.64) | MAPTSMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1876940 | 0.77 | RECQL (0.72) | MAPTSMN1; SMN2RECQLKCNJ1KCNH2 | |
| SCHEMBL15073074 | 0.76 | KCNJ1 (0.49) | MAPTSMN1; SMN2KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL2384676 | 0.76 | RECQL (0.70) | MAPTSMN1; SMN2RECQLKCNJ1KCNH2 | |
| SCHEMBL6607225 | 0.75 | RECQL (0.68) | MAPTSMN1; SMN2RECQLKCNJ1KCNH2 | |
| SCHEMBL4987745 | 0.73 | RECQL (0.67) | MAPTSMN1; SMN2RECQLKCNJ1KCNH2 | |
| SCHEMBL2747017 | 0.73 | KCNJ1 (0.73) | MAPTSMN1; SMN2RECQLKCNJ1KCNH2 | |
| SCHEMBL1578918 | 0.73 | ALDH1A1 (0.48) | MAPTSMN1; SMN2RECQLKCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9352050-B2 | Processes for preparing peptide conjugates and linkers | PFIZER INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-20150031108-A1 | PROCESSES FOR PREPARING PEPTIDE CONJUGATES AND LINKERS | PEPTIDE LOGIC LLC | 2015-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031108-A1 | PROCESSES FOR PREPARING PEPTIDE CONJUGATES AND LINKERS | VIP, NGLY1, PTMS | MAPT 3101/4885SMN1; SMN2 2861/4885RECQL 3892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.