SCHEMBL15074767

SCHEMBL15074767

CCCCCCCCNC(=O)C1COC(=O)O1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.59
NAAA Q02083 1/20 0.49
PRCP P42785 2/20 0.48
GNAI3 P08754 1/20 0.46
GNAO1 P09471 1/20 0.46
GNAI1 P63096 1/20 0.46
EPHX1 P07099 4/20 0.44
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16493476 1.00 HPGD (0.59) HPGDNAAAPRCPGNAI3GNAO1
SCHEMBL16335507 1.00 HPGD (0.59) HPGDNAAAPRCPGNAI3GNAO1
SCHEMBL15057598 0.94 HPGD (0.66) HPGDNAAAPOLB
SCHEMBL15074765 0.92 HPGD (0.51) HPGDNAAAPOLB
SCHEMBL19688989 0.85 HPGD (0.47) HPGDNAAAPOLB
SCHEMBL19688991 0.84 HPGD (0.45) HPGDPOLB
SCHEMBL28144329 0.80 NAAA (0.57) HPGDNAAAPRCPGNAI3GNAO1
SCHEMBL28144355 0.80 NAAA (0.57) HPGDNAAAPRCPGNAI3GNAO1
SCHEMBL2495872 0.80 NAAA (0.57) HPGDNAAAPRCPGNAI3GNAO1
SCHEMBL10536013 0.79 NAAA (0.54) HPGDNAAAPRCPGNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013092011-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-06-27 WO disclosed