Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16493476 | 0.94 | HPGD (0.59) | HPGDPOLBNAAA | |
| SCHEMBL16335507 | 0.94 | HPGD (0.59) | HPGDPOLBNAAA | |
| SCHEMBL15074767 | 0.94 | HPGD (0.59) | HPGDPOLBNAAA | |
| SCHEMBL15074765 | 0.88 | HPGD (0.51) | HPGDPOLBLMNAKMT2AMEN1 | |
| SCHEMBL19688989 | 0.82 | HPGD (0.47) | HPGDPOLBKMT2AMEN1GAA | |
| SCHEMBL19688991 | 0.80 | HPGD (0.45) | HPGDPOLBLMNAKMT2AMEN1 | |
| SCHEMBL15716575 | 0.79 | BCHE (0.56) | HPGDPOLBBCHELMNASMN1; SMN2 | |
| SCHEMBL22198070 | 0.76 | HPGD (0.52) | HPGDBCHELMNASMN1; SMN2KMT2A | |
| SCHEMBL19320497 | 0.76 | POLB (0.42) | HPGDPOLBLMNASMN1; SMN2KMT2A | |
| SCHEMBL10536013 | 0.74 | NAAA (0.54) | HPGDPOLBBCHENAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210324141-A1 | METHOD FOR PRODUCING NON-ISOCYANATE POLYURETHANES | HENKEL AG & CO. KGAA (DE) | 2021-10-21 | — | — | US | disclosed |
| EP-3677616-A1 | METHOD FOR PRODUCING NON-ISOCYANATE POLYURETHANES | Henkel AG & Co. KGaA (DE) | 2020-07-08 | — | — | EP | disclosed |
| EP-3013811-B1 | 2-OXO-1,3-DIOXOLANE-4-ACYL HALIDES, THEIR PREPARATION AND USE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2017-07-12 | — | — | EP | disclosed |
| EP-3013811-B1 | 2-OXO-1,3-DIOXOLANE-4-ACYL HALIDES, THEIR PREPARATION AND USE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2017-07-12 | — | — | EP | disclosed |
| US-9643948-B2 | 2-oxo-1,3-dioxolane-4-acyl halides, their preparation and use | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9643948-B2 | 2-oxo-1,3-dioxolane-4-acyl halides, their preparation and use | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9643948-B2 | 2-oxo-1,3-dioxolane-4-acyl halides, their preparation and use | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2017-05-09 | — | — | US | disclosed |
| EP-2794585-B1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | CONSTR RES & TECH GMBH (DE) | 2016-06-15 | — | — | EP | disclosed |
| EP-2794585-B1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | CONSTR RES & TECH GMBH (DE) | 2016-06-15 | — | — | EP | disclosed |
| US-20160145232-A1 | 2-OXO-1,3-DIOXOLANE-4-ACYL HALIDES, THEIR PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2016-05-26 | — | — | US | disclosed |
| US-20150051365-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2015-02-19 | — | — | US | disclosed |
| US-20150051365-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2015-02-19 | — | — | US | disclosed |
| US-20150051365-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2015-02-19 | — | — | US | disclosed |
| EP-2818465-A1 | 2-Oxo-1,3-dioxolane-4-acyl halides, their preparation and use | Construction Research & Technology GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| WO-2014206636-A1 | 2-OXO-1,3-DIOXOLANE-4-ACYL HALIDES, THEIR PREPARATION AND USE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2014-12-31 | — | — | WO | disclosed |
| EP-2818465-A1 | 2-Oxo-1,3-dioxolane-4-acyl halides, their preparation and use | Construction Research & Technology GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| WO-2014206636-A1 | 2-OXO-1,3-DIOXOLANE-4-ACYL HALIDES, THEIR PREPARATION AND USE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2014-12-31 | — | — | WO | disclosed |
| EP-2794585-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | Construction Research & Technology GmbH (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013092011-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013092011-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210324141-A1 | METHOD FOR PRODUCING NON-ISOCYANATE POLYURETHANES | UROD, IDH3A, SQLE | HPGD 66/4885POLB 1386/4885BCHE 103/4885 |
| US-20160145232-A1 | 2-OXO-1,3-DIOXOLANE-4-ACYL HALIDES, THEIR PREPARATION AND USE | AOX1, AOC2, AOC1 | HPGD 1516/4885POLB 1794/4885BCHE 1148/4885 |
| US-20150051365-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | HAO2, OXGR1, AOX1 | HPGD 170/4885POLB 610/4885BCHE 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.