Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16493476 | 0.92 | HPGD (0.59) | HPGDPOLBNAAA | |
| SCHEMBL15074767 | 0.92 | HPGD (0.59) | HPGDPOLBNAAA | |
| SCHEMBL16335507 | 0.92 | HPGD (0.59) | HPGDPOLBNAAA | |
| SCHEMBL19688991 | 0.91 | HPGD (0.45) | HPGDPOLBMEN1KMT2AGAA | |
| SCHEMBL19688989 | 0.89 | HPGD (0.47) | HPGDPOLBMEN1KMT2AGAA | |
| SCHEMBL15057598 | 0.88 | HPGD (0.66) | HPGDPOLBMEN1KMT2AGAA | |
| SCHEMBL19320497 | 0.80 | POLB (0.42) | HPGDPOLBMEN1KMT2AGAA | |
| SCHEMBL15933869 | 0.79 | GAA (0.39) | HPGDPOLBMEN1KMT2AGAA | |
| SCHEMBL17327999 | 0.78 | GAA (0.36) | HPGDPOLBMEN1KMT2AGAA | |
| SCHEMBL17327998 | 0.78 | GAA (0.36) | HPGDPOLBMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339846-A1 | USE OF COMPOUNDS HAVING N 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE UNITS IN TWO-COMPONENT ADHESIVES | BASF SE (DE) | 2020-10-29 | — | — | US | disclosed |
| US-20200165373-A1 | CURABLE ORGANIC POLYMER COMPRISING AT LEAST ONE ACYLUREA UNIT, ITS PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2020-05-28 | — | — | US | disclosed |
| US-10590227-B2 | Curable organic polymer comprising at least one acylurea unit, its preparation and use | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2020-03-17 | — | — | US | disclosed |
| US-20170253687-A1 | A CURABLE ORGANIC POLYMER COMPRISING AT LEAST ONE ACYLUREA UNIT, ITS PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2017-09-07 | — | — | US | disclosed |
| US-20170008871-A1 | 2-HYDROXYETHYL 2-OXO-1,3-DIOXOLANE-4-CARBOXYLATES, THEIR PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2017-01-12 | — | — | US | disclosed |
| EP-2794585-B1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | CONSTR RES & TECH GMBH (DE) | 2016-06-15 | — | — | EP | disclosed |
| US-9309218-B2 | 2-Oxo-1,3-dioxolane-4-carboxamides, their preparation and use | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| WO-2016041666-A1 | A CURABLE ORGANIC POLYMER COMPRISING AT LEAST ONE ACYLUREA UNIT, ITS PREPARATION AND USE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |
| EP-2998331-A1 | A curable organic polymer comprising at least one acylurea unit, its preparation and use | Construction Research & Technology GmbH (DE) | 2016-03-23 | — | — | EP | disclosed |
| WO-2015132080-A1 | 2-HYDROXYETHYL 2-OXO-1, 3-DIOXOLANE-4-CARBOXYLATES, THEIR PREPARATION AND USE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2015-09-11 | — | — | WO | disclosed |
| EP-2915808-A1 | 2-Hydroxyethyl 2-oxo-1,3-dioxolane-4-carboxylates, their preparation and use | Construction Research & Technology GmbH (DE) | 2015-09-09 | — | — | EP | disclosed |
| US-20150051365-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2015-02-19 | — | — | US | disclosed |
| WO-2013092011-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008871-A1 | 2-HYDROXYETHYL 2-OXO-1,3-DIOXOLANE-4-CARBOXYLATES, THEIR PREPARATION AND USE | HAO2, OXGR1, HAO1 | HPGD 138/4885POLB 1071/4885MEN1 3450/4885 |
| US-20150051365-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | HAO2, OXGR1, AOX1 | HPGD 170/4885POLB 610/4885MEN1 2743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.