Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13411276 | 0.90 | FAAH (0.47) | FAAHCES2CASP2TSHRRECQL | |
| SCHEMBL21096710 | 0.88 | FAAH (0.65) | FAAHACHECASP2TSHRRECQL | |
| SCHEMBL9921405 | 0.88 | FAAH (0.46) | FAAHCES2ACHETSHRRECQL | |
| SCHEMBL16182412 | 0.88 | TSHR (0.56) | FAAHCES2ACHECASP2TSHR | |
| SCHEMBL13857031 | 0.86 | FAAH (0.67) | FAAHCASP2TSHRRECQLEPHX1 | |
| SCHEMBL3273924 | 0.85 | FAAH (0.51) | FAAHACHECASP2TSHRRECQL | |
| SCHEMBL12733561 | 0.84 | CES2 (0.51) | FAAHCES2TSHRRECQL | |
| SCHEMBL13296412 | 0.84 | FAAH (0.55) | FAAHACHECASP2TSHRRECQL | |
| SCHEMBL27986572 | 0.84 | FAAH (0.70) | FAAHCASP2EPHX1KMT2AMEN1 | |
| SCHEMBL19168532 | 0.82 | TSHR (0.56) | FAAHCES2ACHECASP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163227-B2 | Anti-diabetic compounds | COVX TECHNOLOGIES IRELAND LIMITED (IE) | 2015-10-20 | — | — | US | disclosed |
| US-8722622-B2 | FGF21 conjugates and anti-diabetic uses thereof | COVX TECHNOLOGIES IRELAND, LIMITED (IE) | 2014-05-13 | — | — | US | disclosed |
| US-20130164310-A1 | ANTI-DIABETIC COMPOUNDS | COVX TECHNOLOGIES IRELAND LIMITED | 2013-06-27 | — | — | US | disclosed |