Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075515 | 0.90 | FAAH (0.56) | FAAHMEN1KMT2ACES2TSHR | |
| SCHEMBL13411277 | 0.87 | TSHR (0.59) | FAAHMEN1KMT2ATSHRKDM4E | |
| SCHEMBL18057043 | 0.87 | FAAH (0.49) | FAAHMEN1KMT2ACES2KDM4E | |
| SCHEMBL9921405 | 0.85 | FAAH (0.46) | FAAHMEN1KMT2ACES2TSHR | |
| SCHEMBL21501522 | 0.84 | CES2 (0.41) | FAAHMEN1KMT2ACES2TSHR | |
| SCHEMBL16182412 | 0.82 | TSHR (0.56) | FAAHCES2TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL16277091 | 0.82 | FAAH (0.45) | FAAHMEN1KMT2ACES2KDM4E | |
| SCHEMBL13034763 | 0.82 | TSHR (0.43) | FAAHMEN1KMT2ACES2TSHR | |
| SCHEMBL12733561 | 0.82 | CES2 (0.51) | FAAHCES2TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL13531884 | 0.82 | HPGD (0.45) | CES2TSHRKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056543-A1 | POSACONAZOLE POLYMER CONJUGATES AND METHODS OF TREATMENT USING POSACONAZOLE AND POLYMER CONJUGATES THEREOF | ENZON PHARMACEUTICALS, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| US-7625898-B2 | Posaconazole polymer conjugates and methods of treatment using posaconazole and polymer conjugates thereof | ENZON PHARMACEUTICALS, INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-20080171013-A1 | POSACONAZOLE POLYMER CONJUGATES AND METHODS OF TREATMENT USING POSACONAZOLE AND POLYMER CONJUGATES THEREOF | ENZON PHARMACEUTICALS, INC. (US) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171013-A1 | POSACONAZOLE POLYMER CONJUGATES AND METHODS OF TREATMENT USING POSACONAZOLE AND POLYMER CONJUGATES THEREOF | ALG1, DDOST, B3GAT3 | FAAH 4221/4885MEN1 263/4885KMT2A 2622/4885 |
| US-20100056543-A1 | POSACONAZOLE POLYMER CONJUGATES AND METHODS OF TREATMENT USING POSACONAZOLE AND POLYMER CONJUGATES THEREOF | ALG1, DDOST, B3GAT3 | FAAH 4221/4885MEN1 263/4885KMT2A 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.