Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14754389 | 0.84 | CYP1A2 (0.70) | SMN1; SMN2CYP1A2ALDH1A1POLBKMT2A | |
| SCHEMBL15075832 | 0.83 | LMNA (0.51) | SMN1; SMN2HTTRAB9ACYP1A2ALDH1A1 | |
| SCHEMBL15075863 | 0.80 | TP53 (0.51) | SMN1; SMN2HTTCYP1A2ALDH1A1POLB | |
| SCHEMBL15075675 | 0.78 | CYP1A2 (0.46) | SMN1; SMN2CYP1A2ALDH1A1NPSR1ALOX15 | |
| SCHEMBL14754492 | 0.77 | RXFP1 (0.47) | SMN1; SMN2CYP1A2ALDH1A1POLBKMT2A | |
| SCHEMBL19036472 | 0.75 | CNOT7 (0.51) | SMN1; SMN2CYP1A2ALDH1A1POLBMEN1 | |
| SCHEMBL1065735 | 0.74 | LMNA (0.59) | SMN1; SMN2ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL15075818 | 0.73 | CYP1A2 (0.49) | SMN1; SMN2CYP1A2ALDH1A1POLBMEN1 | |
| SCHEMBL12605662 | 0.73 | HTT (0.61) | SMN1; SMN2HTTGALR3RAB9AALDH1A1 | |
| SCHEMBL14754387 | 0.72 | RXFP1 (0.72) | ALDH1A1POLBMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165427-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | HYDRA BIOSCIENCES, INC. (US) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165427-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | SMN1; SMN2 1895/4885HTT 4377/4885GALR3 954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.