SCHEMBL15076560

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15076536	0.96	LMNA (0.52)	LMNAALDH1A1KDM4EGFERTP53
	SCHEMBL15076498	0.90	MAPT (0.56)	LMNAALDH1A1KDM4EGFERTP53
	SCHEMBL15076825	0.90	LMNA (0.53)	LMNAALDH1A1KDM4EGFERTP53
	SCHEMBL15076613	0.89	CYP3A4 (0.57)	LMNAALDH1A1KDM4EGFERTP53
	SCHEMBL15277064	0.89	LMNA (0.49)	LMNAALDH1A1KDM4EGFERTP53
	SCHEMBL15076368	0.88	KMT2A (0.52)	LMNAALDH1A1SMN1; SMN2TSHRHTT
	SCHEMBL15076814	0.86	CYP3A4 (0.56)	LMNAALDH1A1KDM4EGFERTP53
	SCHEMBL15277063	0.86	LMNA (0.51)	LMNAALDH1A1KDM4EGFERTP53
	SCHEMBL15076423	0.86	LMNA (0.53)	LMNAALDH1A1KDM4EGFERTP53
	SCHEMBL15076797	0.85	MAPT (0.51)	LMNATP53SMN1; SMN2ENPP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.