SCHEMBL15076368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15276966	0.94	KMT2A (0.54)	KMT2AMEN1L3MBTL1NPC1LMNA
	SCHEMBL15076355	0.90	KMT2A (0.51)	KMT2AMEN1L3MBTL1NPC1LMNA
	SCHEMBL15076542	0.90	KMT2A (0.58)	KMT2AMEN1L3MBTL1NPC1LMNA
	SCHEMBL15076360	0.89	KMT2A (0.50)	KMT2AMEN1L3MBTL1NPC1LMNA
	SCHEMBL15076318	0.88	KMT2A (0.56)	KMT2AMEN1L3MBTL1NPC1LMNA
	SCHEMBL15076560	0.88	LMNA (0.50)	KMT2ALMNATSHRHSD17B10HTT
	SCHEMBL17084998	0.88	KMT2A (0.49)	KMT2AMEN1L3MBTL1NPC1LMNA
	SCHEMBL15076797	0.87	MAPT (0.51)	KMT2AMEN1NPC1LMNAPOLB
	SCHEMBL15076388	0.86	KMT2A (0.49)	KMT2AMEN1L3MBTL1NPC1HSD17B10
	SCHEMBL19157531	0.85	THRB (0.55)	KMT2AMEN1LMNAPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.