SCHEMBL15076797

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15076420	0.96	MAPT (0.52)	MAPTTP53RAB9ALMNAENPP2
	SCHEMBL19157531	0.93	THRB (0.55)	MAPTTP53LMNAPOLBMEN1
	SCHEMBL15076605	0.90	MAPT (0.52)	MAPTTP53RAB9ALMNAPOLB
	SCHEMBL15076402	0.89	MAPT (0.54)	MAPTTP53RAB9ALMNAENPP2
	SCHEMBL19157176	0.89	MAPT (0.54)	MAPTTP53RAB9ALMNAENPP2
	SCHEMBL15277031	0.89	MAPT (0.48)	MAPTTP53RAB9ALMNAENPP2
	SCHEMBL15076704	0.88	MAPT (0.55)	MAPTTP53LMNAPOLBMEN1
	SCHEMBL15076476	0.88	CYP3A4 (0.57)	MAPTTP53RAB9ALMNAENPP2
	SCHEMBL15076368	0.87	KMT2A (0.52)	MAPTLMNAPOLBMEN1KMT2A
	SCHEMBL15276993	0.86	MAPT (0.53)	MAPTTP53RAB9ALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.