Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15277031 | 0.89 | MAPT (0.48) | MAPTTP53ATAD2CECR2LMNA | |
| SCHEMBL15076619 | 0.86 | LMNA (0.48) | MAPTTP53LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15076602 | 0.85 | MAPT (0.50) | MAPTTP53ATAD2CECR2LMNA | |
| SCHEMBL15076402 | 0.82 | MAPT (0.54) | MAPTTP53LMNARAB9ASMN1; SMN2 | |
| SCHEMBL15076476 | 0.81 | CYP3A4 (0.57) | MAPTTP53LMNARAB9ASMN1; SMN2 | |
| SCHEMBL15076797 | 0.81 | MAPT (0.51) | MAPTTP53LMNARAB9ASMN1; SMN2 | |
| SCHEMBL15076398 | 0.80 | MAPT (0.53) | MAPTTP53LMNARAB9ASMN1; SMN2 | |
| SCHEMBL15076798 | 0.79 | MAPT (0.49) | MAPTTP53ATAD2CECR2LMNA | |
| SCHEMBL19157176 | 0.79 | MAPT (0.54) | MAPTTP53LMNARAB9ASMN1; SMN2 | |
| SCHEMBL15076495 | 0.78 | CYP1A2 (0.56) | MAPTTP53LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096744-A1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |