SCHEMBL1507766

SCHEMBL1507766

COC1([N+](=O)[O-])C=CC(C=Cc2ccccc2)=CC1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.36
TUBB1 Q9H4B7 2/20 0.35
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35
TUBB8 Q3ZCM7 1/20 0.35
TUBA3E Q6PEY2 1/20 0.35
TUBA1A Q71U36 1/20 0.35
TUBA1C Q9BQE3 1/20 0.35
TUBB6 Q9BUF5 1/20 0.35
TUBB2B Q9BVA1 1/20 0.35
NFE2L2 Q16236 5/20 0.35
CYP19A1 P11511 3/20 0.33
TRPA1 O75762 2/20 0.33
PTGS2 P35354 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9089397 0.71 FBP1 (0.36) FBP1TUBB1TUBB4ATUBBTUBA3C
SCHEMBL27844868 0.68 TRPA1 (0.38) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL28874500 0.68
SCHEMBL28503894 0.68
SCHEMBL3661471 0.67 CMA1 (0.38) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL6857278 0.65 NFE2L2 (0.43) FBP1NFE2L2CYP19A1CYP1B1MEN1
SCHEMBL8319755 0.65 GLA (0.36) TRPA1CYP1A2CYP1B1TDP1MEN1
SCHEMBL8930790 0.64 FBP1 (0.40) FBP1NFE2L2CYP19A1CYP1B1MEN1
SCHEMBL1101015 0.64 FBP1 (0.37) FBP1NFE2L2CYP19A1CYP1B1MEN1
SCHEMBL10940951 0.63 FBP1 (0.36) FBP1NFE2L2PTGS2MEN1S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6762844-B2 Optical microscope using an interferometric source of two-color, two-beam entangled photons UT-BATTELLE, LLC 2004-07-13 US claimed
US-6744518-B2 Interferometric source of multi-color, multi-beam entangled photons with mirror and mixer UT-BATTELLE, LLC 2004-06-01 US claimed
US-20030098979-A1 Optical microscope using an interferometric source of two-color, two-beam entangled photons ENERGY, U.S. DEPARTMENT OF 2003-05-29 US claimed
US-20030098980-A1 Interferometric source of multi-color, multi-beam entangled photons UT-BATTELLE, L.L.C. 2003-05-29 US claimed
WO-2003019282-A2 ENTANGLED-PHOTON MICROSCOPE UT-BATTELLE, LLC (US) 2003-03-06 WO claimed
WO-2003019284-A2 INTERFEROMETRIC SOURCE OF MULTI-COLOR, MULTI-BEAM ENTANGLED PHOTONS UT-BATTELLE, LLC (US) 2003-03-06 WO claimed
EP-2299310-A2 Electro-active semifinished lens blank E-Vision, LLC (US) 2011-03-23 EP disclosed
CN-1227559-C System, apparatus and method for correcting vision using electro-active lenses E VISION LLC (US) 2005-11-16 CN disclosed
CN-1662172-A Electro-active multi-focal spectacle lens E VISION LLC (US) 2005-08-31 CN disclosed
CN-1653374-A Electro-optic lens with integrated components E VISION LLC (US) 2005-08-10 CN disclosed
US-6762844-B2 Optical microscope using an interferometric source of two-color, two-beam entangled photons UT-BATTELLE, LLC 2004-07-13 US disclosed
US-6744518-B2 Interferometric source of multi-color, multi-beam entangled photons with mirror and mixer UT-BATTELLE, LLC 2004-06-01 US disclosed
US-6678054-B1 Quantum channel for the transmission of information UT-BATTELLE, L.L.C. 2004-01-13 US disclosed
US-20030098979-A1 Optical microscope using an interferometric source of two-color, two-beam entangled photons ENERGY, U.S. DEPARTMENT OF 2003-05-29 US disclosed
US-20030098980-A1 Interferometric source of multi-color, multi-beam entangled photons UT-BATTELLE, L.L.C. 2003-05-29 US disclosed
WO-2003019283-A2 INTERFEROMETRIC SOURCE OF MULTI-COLOR, MULTI-BEAM ENTAGLED PHOTONS UT-BATTELLE, LLC (US) 2003-03-06 WO disclosed
WO-2003019282-A2 ENTANGLED-PHOTON MICROSCOPE UT-BATTELLE, LLC (US) 2003-03-06 WO disclosed
WO-2003019284-A2 INTERFEROMETRIC SOURCE OF MULTI-COLOR, MULTI-BEAM ENTANGLED PHOTONS UT-BATTELLE, LLC (US) 2003-03-06 WO disclosed
CN-1372650-A System, apparatus and method for correcting vision using electro-active lenses E VISION LLC (US) 2002-10-02 CN disclosed
WO-1991003458-A1 NONLINEAR OPTICAL DEVICE FROM 3-METHYL-4-METHOXY-4'-NITROSTILBENE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-21 WO disclosed