Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.82 |
| ▸ | GLA | P06280 | 1/20 | 0.82 |
| ▸ | SLC9A1 | P19634 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14796568 | 0.84 | SLC9A1 (0.79) | TSHRGLASLC9A1NPC1RAB9A | |
| SCHEMBL8653684 | 0.80 | SLC9A1 (0.71) | TSHRGLASLC9A1NPC1RAB9A | |
| SCHEMBL30360007 | 0.80 | TSHR (0.70) | TSHRGLASLC9A1NPC1RAB9A | |
| SCHEMBL285179 | 0.80 | TSHR (0.70) | TSHRGLASLC9A1NPC1RAB9A | |
| SCHEMBL730645 | 0.78 | SLC9A1 (0.70) | TSHRGLASLC9A1NPC1RAB9A | |
| SCHEMBL7011474 | 0.78 | SLC9A1 (0.70) | TSHRGLASLC9A1NPC1RAB9A | |
| SCHEMBL29482278 | 0.78 | SLC9A1 (0.70) | TSHRGLASLC9A1NPC1RAB9A | |
| SCHEMBL1834794 | 0.78 | SLC9A1 (1.00) | TSHRGLASLC9A1NPC1RAB9A | |
| SCHEMBL7667065 | 0.78 | SLC9A1 (0.70) | TSHRGLASLC9A1NPC1RAB9A | |
| SCHEMBL7667067 | 0.78 | SLC9A1 (0.70) | TSHRGLASLC9A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013092556-A1 | METAL-CHELATING COMPOUNDS HAVING AT LEAST ONE POLYAMINO CHAIN | UNIVERSITE DE RENNES I (FR) | 2013-06-27 | — | — | WO | disclosed |