SCHEMBL15078747

SCHEMBL15078747

O=C(O)CCc1ccc(N(c2ccccc2)c2ccc(Br)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 14/20 0.58
KEAP1 Q14145 1/20 0.56
FFAR4 Q5NUL3 7/20 0.55
PDPK1 O15530 1/20 0.50
IDO1 P14902 1/20 0.48
PPARD Q03181 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30990549 0.95 FFAR1 (0.59) FFAR1KEAP1FFAR4PDPK1IDO1
SCHEMBL25933402 0.92 FFAR1 (0.68) FFAR1KEAP1FFAR4
SCHEMBL11437198 0.92 FFAR1 (0.68) FFAR1KEAP1FFAR4
SCHEMBL14732629 0.90 FFAR1 (0.71) FFAR1KEAP1FFAR4PPARD
SCHEMBL279262 0.87 FFAR1 (0.73) FFAR1KEAP1FFAR4
SCHEMBL17321106 0.87 FFAR1 (0.73) FFAR1KEAP1FFAR4
SCHEMBL14732640 0.84 FFAR1 (0.67) FFAR1KEAP1FFAR4PPARD
SCHEMBL5455 0.84 FFAR1 (0.71) FFAR1KEAP1FFAR4PDPK1IDO1
SCHEMBL11887474 0.84 IDO1 (0.52) FFAR1FFAR4PDPK1IDO1
SCHEMBL279537 0.83 FFAR1 (0.79) FFAR1KEAP1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9188886-B2 Image holding member for image forming apparatus, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-17 US disclosed
US-8936858-B2 Organic electroluminescent element and display FUJI XEROX CO., LTD. (JP) 2015-01-20 US disclosed
US-8900726-B2 2014-12-02 US disclosed
US-20140227005-A1 IMAGE HOLDING MEMBER FOR IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-08-14 US disclosed
US-8741515-B2 Image holding member for image forming apparatus, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-06-03 US disclosed
US-20130164663-A1 IMAGE HOLDING MEMBER FOR IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-06-27 US disclosed