Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 5/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | POLQ | O75417 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19879909 | 0.89 | ALDH1A1 (0.48) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL11770773 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL1239045 | 0.84 | KMT2A (0.51) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL1760632 | 0.83 | KMT2A (0.58) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL6107716 | 0.82 | KMT2A (0.47) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL11635095 | 0.82 | RAB9A (0.46) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL5351542 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL6247670 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL9322466 | 0.81 | KMT2A (0.46) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL9760007 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2ANPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260049-B | Method for preparing 2-chloro-N-methylacetanilide by taking wheat straw lignin as raw material | 宿州学院 | 2023-11-07 | — | — | CN | claimed |
| CN-115260049-A | Method for preparing 2-chloro-N-methylacetanilide by taking wheat straw lignin as raw material | 宿州学院 | 2022-11-01 | — | — | CN | claimed |
| JP-58049349-A | — | — | None | — | — | JP | disclosed |
| EP-4347568-A1 | HETEROARYL DIAMIDE IRE1/XBP1S ACTIVATORS | Protego Biopharma, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| US-20240092757-A1 | HETEROARYL DIAMIDE IRE1/XBP1s ACTIVATORS | THE SCRIPPS RESEARCH INSTITUTE | 2024-03-21 | — | — | US | disclosed |
| US-20240018135-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF | MEDIFRON DBT INC. (KR) | 2024-01-18 | — | — | US | disclosed |
| US-20240018135-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF | MEDIFRON DBT INC. (KR) | 2024-01-18 | — | — | US | disclosed |
| US-20240018135-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF | MEDIFRON DBT INC. (KR) | 2024-01-18 | — | — | US | disclosed |
| CN-115260049-B | Method for preparing 2-chloro-N-methylacetanilide by taking wheat straw lignin as raw material | 宿州学院 | 2023-11-07 | — | — | CN | disclosed |
| CN-115260049-B | Method for preparing 2-chloro-N-methylacetanilide by taking wheat straw lignin as raw material | 宿州学院 | 2023-11-07 | — | — | CN | disclosed |
| CN-115260049-B | Method for preparing 2-chloro-N-methylacetanilide by taking wheat straw lignin as raw material | 宿州学院 | 2023-11-07 | — | — | CN | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |
| US-4399285-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4391629-A | PLANT GROWTH REGULATORS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-07-05 | — | — | US | disclosed |
| JP-S5849349-A | CHLOROACETANILIDE DERIVATIVE AND HERBICIDE CONTAINING IT | KUMIAI CHEM IND CO LTD | 1983-03-23 | — | — | JP | disclosed |
| US-4345938-A | ESPECIALLY USEFUL FOR WEEDS ASSOCIATED WITH RICE | MONSANTO COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| US-4334073-A | BASIC CATALYSTS, DEACETYLATION, ESTERIFICATION | BAYER AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |
| US-4116964-A | 2-[(N-2-pyridylcarbamoyl)methyl]saccharin | WARNER-LAMBERT COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-4099954-A | Amide phosphorothiolate herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-07-11 | — | — | US | disclosed |
| US-4074048-A | Process for the preparation of 4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides | WARNER-LAMBERT COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092757-A1 | HETEROARYL DIAMIDE IRE1/XBP1s ACTIVATORS | XBP1, HSPA5, DNAJC10 | ALDH1A1 2884/4885KMT2A 4215/4885NPC1 509/4885 |
| US-20240018135-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF | OGA, OGT, ENGASE | ALDH1A1 1141/4885KMT2A 1493/4885NPC1 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.