Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 3/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597828 | 0.94 | NAALAD2 (0.57) | NAALAD2MEN1KMT2AL3MBTL1CA1 | |
| Sulfuric Acid SCHEMBL1507951 | 0.88 | MMP2 (0.52) | NAALAD2CA1CA2MME | |
| SCHEMBL2214359 | 0.82 | FOLH1 (0.55) | NAALAD2MEN1KMT2AL3MBTL1CA1 | |
| SCHEMBL10778599 | 0.82 | FOLH1 (0.55) | NAALAD2MEN1KMT2AL3MBTL1CA1 | |
| SCHEMBL2214358 | 0.82 | FOLH1 (0.55) | NAALAD2MEN1KMT2AL3MBTL1CA1 | |
| SCHEMBL31538191 | 0.81 | FOLH1 (0.51) | NAALAD2MEN1KMT2AL3MBTL1CA1 | |
| SCHEMBL8393439 | 0.81 | FOLH1 (0.55) | NAALAD2MEN1KMT2AL3MBTL1CA1 | |
| SCHEMBL1507973 | 0.81 | KDM4E (0.46) | MEN1KMT2AL3MBTL1CA2 | |
| SCHEMBL547297 | 0.80 | NAALAD2 (0.55) | NAALAD2L3MBTL1FOLH1MMECPA1 | |
| SCHEMBL1272029 | 0.80 | NAALAD2 (0.55) | NAALAD2L3MBTL1FOLH1MMECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289970-B1 | Biocompatible polymers | BARRITAULT DENIS (FR) | 2015-05-20 | — | — | EP | disclosed |
| EP-1117695-B1 | BIOCOMPATIBLE POLYMERS, COMPOSITIONS CONTAINING SAME AND THEIR USE FOR THE MANUFACTURE OF DRUGS | BARRITAULT DENIS (FR) | 2015-05-20 | — | — | EP | disclosed |
| EP-2289970-A1 | Biocompatible polymers, their process of manufacture and compositions containing them | Barritault, Denis (FR) | 2011-03-02 | — | — | EP | disclosed |
| EP-1117695-A1 | BIOCOMPATIBLE POLYMERS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | Barritault, Denis (FR) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000005270-A1 | BIOCOMPATIBLE POLYMERS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | BARRITAULT DENIS (FR) | 2000-02-03 | — | — | WO | disclosed |