SCHEMBL1507973

SCHEMBL1507973

O=C(O)CN[C@@H](Cc1ccc(OS(=O)(=O)O)cc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
KDM4A O75164 1/20 0.46
ITGB3 P05106 4/20 0.42
ITGA2B P08514 4/20 0.42
CA2 P00918 1/20 0.41
LDHA P00338 1/20 0.39
MMP2 P08253 5/20 0.38
MMP9 P14780 4/20 0.38
ADAMTS4 O75173 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17111996 0.83 ITGB3 (0.49) KDM4EKDM4AITGB3ITGA2BCA2
SCHEMBL10987492 0.82 ITGB1 (0.48) KDM4EKDM4AITGB3ITGA2BMMP2
SCHEMBL28382375 0.81 LDHA (0.61) CA2LDHAMMP2MMP9KMT2A
Sulfuric Acid SCHEMBL1507970 0.81 NAALAD2 (0.52) CA2MEN1KMT2AL3MBTL1
Sulfuric Acid SCHEMBL1507951 0.81 MMP2 (0.52) CA2MMP2MMP9ADAMTS4
SCHEMBL3091721 0.81 ITGB3 (0.58) KDM4EKDM4AITGB3ITGA2BCA2
SCHEMBL8910599 0.80 KDM4E (0.46) KDM4EKDM4AITGB3ITGA2BCA2
SCHEMBL7597828 0.77 NAALAD2 (0.57) CA2MEN1KMT2AL3MBTL1
SCHEMBL1272029 0.77 NAALAD2 (0.55) MMP2MMP9L3MBTL1
SCHEMBL547297 0.77 NAALAD2 (0.55) MMP2MMP9L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2289970-B1 Biocompatible polymers BARRITAULT DENIS (FR) 2015-05-20 EP disclosed
EP-1117695-B1 BIOCOMPATIBLE POLYMERS, COMPOSITIONS CONTAINING SAME AND THEIR USE FOR THE MANUFACTURE OF DRUGS BARRITAULT DENIS (FR) 2015-05-20 EP disclosed
EP-2289970-A1 Biocompatible polymers, their process of manufacture and compositions containing them Barritault, Denis (FR) 2011-03-02 EP disclosed
EP-1117695-A1 BIOCOMPATIBLE POLYMERS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME Barritault, Denis (FR) 2001-07-25 EP disclosed
WO-2000005270-A1 BIOCOMPATIBLE POLYMERS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME BARRITAULT DENIS (FR) 2000-02-03 WO disclosed