Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508058 | 0.78 | MRGPRX4 (0.52) | MRGPRX4MMP2MMP9MMP14ADAM17 | |
| SCHEMBL13462733 | 0.78 | MRGPRX4 (0.58) | MRGPRX4MMP2MMP9MMP14ADAM17 | |
| SCHEMBL3959704 | 0.76 | TRPM8 (0.51) | — | |
| SCHEMBL3375496 | 0.75 | MRGPRX4 (0.62) | MRGPRX4MMP2MMP9MMP14ADAM17 | |
| SCHEMBL3956819 | 0.74 | KDM4E (0.47) | PPARDPPARATP53SMN1; SMN2 | |
| SCHEMBL6396442 | 0.74 | PPARA (0.48) | PPARDPPARASMN1; SMN2 | |
| SCHEMBL4451916 | 0.73 | PPARA (0.46) | PPARDPPARASMN1; SMN2 | |
| SCHEMBL15936281 | 0.73 | MRGPRX4 (0.57) | MRGPRX4MMP2MMP9MMP14ADAM17 | |
| SCHEMBL15936282 | 0.73 | MRGPRX4 (0.57) | MRGPRX4MMP2MMP9MMP14ADAM17 | |
| SCHEMBL1508368 | 0.73 | FFAR1 (0.77) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289868-A1 | CARBOXYLIC ACID COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2011-03-02 | — | — | EP | disclosed |